Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTO1 | P78417 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.35 |
| ▸ | CCR2 | P41597 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SLC12A2 | P55011 | 1/20 | 0.33 |
| ▸ | SLC12A5 | Q9H2X9 | 1/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.33 |
| ▸ | ATXN2 | Q99700 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12918420 | 0.86 | ADRA1D (0.46) | GSTO1GLAADRA1DCCR2L3MBTL1 | |
| SCHEMBL1013610 | 0.80 | GSTO1 (0.44) | GSTO1GLACCR2L3MBTL1LMNA | |
| SCHEMBL1015882 | 0.80 | GSTO1 (0.44) | GSTO1GLACCR2L3MBTL1LMNA | |
| SCHEMBL2760608 | 0.77 | TAAR1 (0.56) | GSTO1GLAL3MBTL1TSHR | |
| SCHEMBL2760659 | 0.77 | GSTO1 (0.44) | GSTO1GLACCR2LMNAALDH1A1 | |
| SCHEMBL28945097 | 0.77 | GSTO1 (0.44) | GSTO1GLACCR2L3MBTL1LMNA | |
| SCHEMBL48740 | 0.76 | GSTO1 (0.41) | GSTO1GLAADRA1DCCR2L3MBTL1 | |
| SCHEMBL2760747 | 0.75 | SLC6A4 (0.43) | GSTO1ADRA1DCCR2LMNAALDH1A1 | |
| SCHEMBL1780435 | 0.74 | IDO1 (0.54) | L3MBTL1LMNATSHRALDH1A1 | |
| SCHEMBL6212368 | 0.74 | ALDH1A1 (0.55) | L3MBTL1LMNAHPGDTSHRMCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2262766-A2 | AMIDE COMPOUNDS, COMPOSITIONS AND USES THEREOF | Renovis, Inc. (US) | 2010-12-22 | — | — | EP | disclosed |
| WO-2009110985-A2 | AMIDE COMPOUNDS, COMPOSITIONS AND USES THEREOF | RENOVIS, INC. (US) | 2009-09-11 | — | — | WO | disclosed |