Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 2/20 | 0.49 |
| ▸ | RXRA | P19793 | 5/20 | 0.46 |
| ▸ | RXRB | P28702 | 5/20 | 0.46 |
| ▸ | FABP1 | P07148 | 1/20 | 0.44 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CTRC | Q99895 | 1/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.40 |
| ▸ | RXRG | P48443 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.39 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.39 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16418271 | 0.88 | DHODH (0.49) | DHODHRXRARXRBFABP1P2RY14 | |
| SCHEMBL2760718 | 0.85 | DHODH (0.46) | DHODHRXRARXRBFABP1P2RY14 | |
| SCHEMBL2760860 | 0.83 | DHODH (0.52) | DHODHRXRARXRBFABP1P2RY14 | |
| SCHEMBL1495693 | 0.79 | DHODH (0.52) | DHODHRXRARXRBFABP1P2RY14 | |
| SCHEMBL2760813 | 0.79 | DHODH (0.41) | DHODHRXRARXRBFABP1P2RY14 | |
| SCHEMBL16196117 | 0.79 | DHODH (0.70) | DHODHRXRARXRBFABP1P2RY14 | |
| SCHEMBL1495453 | 0.79 | DHODH (0.70) | DHODHRXRARXRBFABP1P2RY14 | |
| SCHEMBL16418270 | 0.79 | GAA (0.51) | DHODHRXRARXRBALDH1A1ADRB3 | |
| SCHEMBL3068080 | 0.78 | DHODH (0.48) | DHODHRXRARXRBFABP1P2RY14 | |
| SCHEMBL2778738 | 0.78 | P2RX3 (0.47) | DHODHALDH1A1LMNAKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150266822-A1 | Amide Compounds, Compositions And Uses Thereof | RENOVIS, INC. | 2015-09-24 | — | — | US | claimed |
| CN-104058999-A | Amide Compounds, Compositions And Uses Thereof | RENOVIS INC | 2014-09-24 | — | — | CN | claimed |
| EP-2262766-A2 | AMIDE COMPOUNDS, COMPOSITIONS AND USES THEREOF | Renovis, Inc. (US) | 2010-12-22 | — | — | EP | claimed |
| WO-2009110985-A2 | AMIDE COMPOUNDS, COMPOSITIONS AND USES THEREOF | RENOVIS, INC. (US) | 2009-09-11 | — | — | WO | claimed |
| US-20150266822-A1 | Amide Compounds, Compositions And Uses Thereof | RENOVIS, INC. | 2015-09-24 | — | — | US | disclosed |
| US-8946439-B2 | Amide compounds, compositions and uses thereof | EVOTEC AG (DE) | 2015-02-03 | — | — | US | disclosed |
| CN-104058999-A | Amide Compounds, Compositions And Uses Thereof | RENOVIS INC | 2014-09-24 | — | — | CN | disclosed |
| CN-104016907-A | Amide compounds, compositions and uses thereof | RENOVIS INC | 2014-09-03 | — | — | CN | disclosed |
| EP-2262766-A2 | AMIDE COMPOUNDS, COMPOSITIONS AND USES THEREOF | Renovis, Inc. (US) | 2010-12-22 | — | — | EP | disclosed |
| WO-2009110985-A2 | AMIDE COMPOUNDS, COMPOSITIONS AND USES THEREOF | RENOVIS, INC. (US) | 2009-09-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150266822-A1 | Amide Compounds, Compositions And Uses Thereof | IL1B, ADORA2B, AVPR1B | DHODH 3626/4885RXRA 380/4885RXRB 103/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.