SCHEMBL27608397

SCHEMBL27608397

COC(C)Cn1c(=O)cc[nH]c1=O

nearest known ligand 0.44

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 1/20 0.33
MPO P05164 1/20 0.33
PDE4B Q07343 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28861793 0.82 TSHR (0.43) PDE4B
SCHEMBL16039139 0.81 TYMP (0.33)
SCHEMBL667079 0.79 ALDH1A1 (0.33) OPRM1MPO
SCHEMBL26779814 0.78 TSHR (0.40) OPRM1MPO
SCHEMBL16037610 0.77 TYMP (0.36) OPRM1MPO
SCHEMBL19064904 0.77 TYMP (0.36) OPRM1MPO
SCHEMBL16247195 0.77 APAF1 (0.46)
SCHEMBL16039559 0.76 TYMP (0.33)
SCHEMBL16039614 0.76 TYMP (0.33)
SCHEMBL7231380 0.75 CDK4 (0.34) OPRM1MPO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1703422-A Meth1 and meth2 polynucleotides and polypeptides HUMAN GENOME SCIENCES INC (US) 2005-11-30 CN disclosed