SCHEMBL667079

SCHEMBL667079

CC(N)Cn1c(=O)cc[nH]c1=O

nearest known ligand 0.46

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.33
GRIK1 P39086 1/20 0.32
GRIA1 P42261 1/20 0.32
HTR2C P28335 9/20 0.32
HTR2A P28223 8/20 0.32
OPRM1 P35372 1/20 0.31
MPO P05164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28861793 0.85 TSHR (0.43) ALDH1A1
SCHEMBL26779814 0.81 TSHR (0.40) ALDH1A1GRIA1OPRM1MPO
SCHEMBL27608397 0.79 OPRM1 (0.33) OPRM1MPO
SCHEMBL5282402 0.79 GRIA1 (0.51) ALDH1A1GRIK1GRIA1
SCHEMBL11705032 0.76 GRIN1 (0.40)
SCHEMBL1923337 0.75 CYP1A2 (0.44) ALDH1A1
SCHEMBL4372132 0.75 CCR8 (0.32) ALDH1A1
SCHEMBL4348692 0.74 ADRA1D (0.37) OPRM1MPO
SCHEMBL26779812 0.74 CDK4 (0.39) ALDH1A1
SCHEMBL26779833 0.74 CDK4 (0.39) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 634 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260138999-A1 REAGENTS AND THEIR USE FOR MODULAR ENANTIODIVERGENT SYNTHESIS OF C-P BONDS BRISTOL MYERS SQUIBB CO (US) 2026-05-21 US disclosed
WO-2026106956-A1 DISULFIDE-STABILIZED NOROVIRUS VIRUS-LIKE PARTICLE DESIGN MERCK SHARP & DOHME LLC (US) 2026-05-21 WO disclosed
US-12629412-B2 Betacoronavirus mRNA vaccines MODERNATX, INC. (US) 2026-05-19 US disclosed
US-20260130985-A1 NUCLEIC ACID-BASED UNIVERSAL VACCINE AND METHODS OF USE THEREOF ADVANCED RNA VACCINE ARV TECH INC (US) 2026-05-14 US disclosed
US-12622960-B2 Varicella zoster virus (VZV) vaccine MODERNATX, INC. (US) 2026-05-12 US disclosed
US-20260108595-A1 BETACORONAVIRUS mRNA VACCINES MODERNATX, INC. (US) 2026-04-23 US disclosed
EP-3458081-B1 POLYNUCLEOTIDES ENCODING CITRIN FOR THE TREATMENT OF CITRULLINEMIA TYPE 2 MODERNATX INC (US) 2026-04-15 EP disclosed
US-20260097110-A1 BETACORONAVIRUS mRNA VACCINES MODERNATX, INC. (US) 2026-04-09 US disclosed
US-20260091104-A1 NUCLEIC ACID VACCINES MODERNATX, INC. (US) 2026-04-02 US disclosed
EP-4709417-A2 POLYNUCLEOTIDES ENCODING NOROVIRUS VP1 ANTIGENS AND USES THEREOF Merck Sharp & Dohme LLC (US) 2026-03-18 EP disclosed
US-20120046346-A1 SUSTAINED POLYPEPTIDE EXPRESSION FROM SYNTHETIC, MODIFIED RNAS AND USES THEREOF IMMUNE DISEASE INSTITUTE, INC. (US) 2012-02-23 US disclosed
WO-2011130624-A2 SUSTAINED POLYPEPTIDE EXPRESSION FROM SYNTHETIC, MODIFIED RNAS AND USES THEREOF IMMUNE DISEASE INSTITUTE, INC. (US) 2011-10-20 WO disclosed
WO-2011103137-A1 CELL-BASED METHODS AND REAGENTS ALNYLAM PHARMACEUTICALS, INC. (US) 2011-08-25 WO disclosed
US-20110150894-A1 METHODS OF MODULATING ANGIOGENESIS VIA TRPV4 CHILDREN'S MEDICAL CENTER CORPORATION (US) 2011-06-23 US disclosed
WO-2011005765-A1 BIOPROCESSING ALNYLAM PHARMACEUTICALS, INC. (US) 2011-01-13 WO disclosed
WO-2011005786-A2 COMPOSITIONS AND METHODS FOR ENHANCING PRODUCTION OF A BIOLOGICAL PRODUCT ALNYLAM PHARMACEUTICALS, INC. (US) 2011-01-13 WO disclosed
WO-2011005793-A1 CELL-BASED BIOPROCESSING ALNYLAM PHARMACEUTICALS, INC. (US) 2011-01-13 WO disclosed
WO-2009155504-A9 METHODS FOR THE MODULATION OF ANGIOGENESIS THE CHILDREN'S MEDICAL CENTER CORPORATION (US) 2010-04-08 WO disclosed
WO-2009155504-A2 METHODS FOR THE MODULATION OF ANGIOGENESIS THE CHILDREN'S MEDICAL CENTER CORPORATION (US) 2009-12-23 WO disclosed
WO-2009149239-A1 METHODS OF MODULATING ANGIOGENESIS VIA TRPV4 CHILDREN'S MEDICAL CENTER CORPORATION (US) 2009-12-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260097110-A1 BETACORONAVIRUS mRNA VACCINES RNMT, RNGTT, METTL16 ALDH1A1 4724/4885GRIK1 4859/4885GRIA1 4764/4885
US-20260138999-A1 REAGENTS AND THEIR USE FOR MODULAR ENANTIODIVERGENT SYNTHESIS OF C-P BONDS RNGTT, CDA, DCTD ALDH1A1 2053/4885GRIK1 4808/4885GRIA1 4381/4885
US-12629412-B2 Betacoronavirus mRNA vaccines RNMT, RNGTT, METTL16 ALDH1A1 4705/4885GRIK1 4845/4885GRIA1 4670/4885
US-20260091104-A1 NUCLEIC ACID VACCINES RNMT, NSUN2, AMPD1 ALDH1A1 3617/4885GRIK1 4839/4885GRIA1 4806/4885
US-20260108595-A1 BETACORONAVIRUS mRNA VACCINES RNMT, METTL16, NSUN2 ALDH1A1 4565/4885GRIK1 4308/4885GRIA1 3431/4885
US-12622960-B2 Varicella zoster virus (VZV) vaccine NSUN2, RNMT, RNGTT ALDH1A1 4802/4885GRIK1 4013/4885GRIA1 3728/4885
US-20260130985-A1 NUCLEIC ACID-BASED UNIVERSAL VACCINE AND METHODS OF USE THEREOF UPF1, NSUN2, CD4 ALDH1A1 4843/4885GRIK1 4253/4885GRIA1 3734/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.