Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 9/20 | 0.44 |
| ▸ | MAPK13 | O15264 | 4/20 | 0.42 |
| ▸ | MAPK12 | P53778 | 4/20 | 0.42 |
| ▸ | MAPK11 | Q15759 | 4/20 | 0.42 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.38 |
| ▸ | HTR3A | P46098 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | MMP12 | P39900 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | BUB1 | O43683 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6275690 | 0.84 | HTR3A (0.53) | MAPK14MAPK13MAPK12MAPK11CD274 | |
| SCHEMBL27627887 | 0.72 | MAPK14 (0.44) | MAPK14MAPK13MAPK12MAPK11HTR3A | |
| SCHEMBL27627894 | 0.72 | MAPK14 (0.44) | MAPK14MAPK13MAPK12MAPK11HTR3A | |
| SCHEMBL27608556 | 0.72 | MAPK14 (0.52) | MAPK14MAPK13MAPK12MAPK11HTR3A | |
| SCHEMBL27627904 | 0.69 | HTR3A (0.68) | MAPK14MAPK13MAPK12MAPK11HTR3A | |
| SCHEMBL6370938 | 0.69 | HTR3A (0.56) | MAPK14MAPK13MAPK12MAPK11CD274 | |
| SCHEMBL6219428 | 0.67 | MAPK14 (0.48) | MAPK14MAPK13MAPK12MAPK11CD274 | |
| SCHEMBL27608554 | 0.66 | MAPK14 (0.46) | MAPK14MAPK13MAPK12MAPK11HTR3A | |
| SCHEMBL6653067 | 0.66 | CYP3A4 (0.47) | MAPK14MAPK13MAPK12MAPK11CYP2C9 | |
| SCHEMBL6371003 | 0.66 | HTR3A (0.53) | MAPK14MAPK13MAPK12MAPK11CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1701069-A | 3,4-disubstituted pyrroles and their for use in treating inflammatory diseases | JANSSEN PHARMACEUTICA NV (BE) | 2005-11-23 | — | — | CN | disclosed |