Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
| ▸ | MMP1 | P03956 | 5/20 | 0.42 |
| ▸ | MMP2 | P08253 | 5/20 | 0.42 |
| ▸ | MMP9 | P14780 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7191119 | 0.84 | BTK (0.49) | MAPTGAALMNAHTTHSD17B10 | |
| SCHEMBL8641397 | 0.81 | MMP1 (0.61) | MAPTGAALMNAHTTNPC1 | |
| SCHEMBL18010920 | 0.81 | HSD17B10 (0.53) | MAPTGAALMNAHTTHSD17B10 | |
| SCHEMBL5725423 | 0.79 | ALDH1A1 (0.57) | MAPTGAALMNAHTTHSD17B10 | |
| SCHEMBL27479697 | 0.76 | NPC1 (0.64) | MAPTGAALMNAHTTHSD17B10 | |
| SCHEMBL28031204 | 0.76 | ESR2 (0.47) | MAPTGAALMNAHTTHSD17B10 | |
| SCHEMBL5866194 | 0.75 | HSP90AA1 (0.46) | LMNAHTTHSD17B10NPC1TP53 | |
| SCHEMBL8403273 | 0.74 | HTT (0.48) | MAPTGAALMNAHTTHSD17B10 | |
| SCHEMBL7924678 | 0.74 | HSD17B10 (0.46) | MAPTLMNAHTTHSD17B10NPC1 | |
| SCHEMBL5723835 | 0.74 | POLB (0.64) | MAPTLMNAHTTHSD17B10NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100413860-C | piperidine derivatives as NMDA receptor antagonists | HUNGARY GIREL GYOGYSZERGYAR (HU) | 2008-08-27 | — | — | CN | disclosed |
| CN-1556805-A | piperidine derivatives as NMDA receptor antagonists | ������ҩ������˾ | 2004-12-22 | — | — | CN | disclosed |