Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | JAK2 | O60674 | 1/20 | 0.48 |
| ▸ | KLK7 | P49862 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PDK1 | Q15118 | 5/20 | 0.44 |
| ▸ | PDK2 | Q15119 | 5/20 | 0.44 |
| ▸ | PDK3 | Q15120 | 5/20 | 0.44 |
| ▸ | PDK4 | Q16654 | 5/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6029980 | 0.84 | PDK1 (0.53) | HTTMAPTTP53JAK2KLK7 | |
| SCHEMBL6367216 | 0.83 | SMN1; SMN2 (0.56) | HTTMAPTTP53JAK2KLK7 | |
| SCHEMBL7299817 | 0.82 | GAA (0.56) | HTTMAPTTP53JAK2KLK7 | |
| SCHEMBL994038 | 0.81 | PDK1 (0.53) | HTTMAPTTP53JAK2KLK7 | |
| SCHEMBL18010920 | 0.80 | HSD17B10 (0.53) | HTTMAPTTP53LMNANPC1 | |
| SCHEMBL5725423 | 0.78 | ALDH1A1 (0.57) | HTTMAPTTP53LMNANPC1 | |
| SCHEMBL28316791 | 0.78 | POLB (0.57) | HTTMAPTTP53JAK2KLK7 | |
| SCHEMBL10562497 | 0.77 | MAPT (0.46) | HTTMAPTTP53JAK2KLK7 | |
| SCHEMBL8203681 | 0.77 | MAPT (0.41) | HTTMAPTTP53JAK2KLK7 | |
| SCHEMBL914296 | 0.77 | PDK1 (0.70) | HTTMAPTTP53JAK2KLK7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5965595-A | SIDE EFFECT REDUCTION; TREATING NASAL CONGESTION AND OTHER ALPHA-2 ADRENORECEPTOR MODULATED DISORDERS, WILL NOT CAUSE HYPERTENSION | THE PROCTER & GAMBLE COMPANY (US) | 1999-10-12 | — | — | US | disclosed |
| US-5914342-A | 2-imidazolinylamino heterocyclic compounds useful as alpha-2 adrenoceptor agonists | THE PROCTER & GAMBLE COMPANY (US) | 1999-06-22 | — | — | US | disclosed |
| US-5663189-A | RESPIRATORY, EYES, GASTROINTESTINAL | THE PROCTER & GAMBLE COMPANY (US) | 1997-09-02 | — | — | US | disclosed |
| EP-0269914-B1 | COMPOSITION AND PROCESS FOR THE OXIDATIVE DYEING OF HAIR ON THE BASIS OF 3-(2',2',2'-TRIFLUORETHYL)AMINOPHENOL DERIVATIVES, AND 3-(2',2',2'-TRIFLUORETHYL)AMINOPHENOL DERIVATIVES | Wella Aktiengesellschaft (DE) | 1991-06-12 | — | — | EP | disclosed |
| WO-1988004166-A1 | HAIR DYEING OXIDISING AGENT AND PROCESS WITH 3-(2',2',2'-TRIFLUOROETHYL)AMINO-PHENOL DERIVATES AND NEW 3-(2',2',2'-TRIFLUOROETHYL)AMINO-PHENOL DERIVATES | WELLA AKTIENGESELLSCHAFT (DE) | 1988-06-16 | — | — | WO | disclosed |