Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 3/20 | 0.65 |
| ▸ | MGLL | Q99685 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.46 |
| ▸ | NAAA | Q02083 | 1/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | MMP12 | P39900 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6166293 | 0.83 | PTPN1 (0.61) | ENPP2MGLLNPC1RAB9AHDAC1 | |
| SCHEMBL1163050 | 0.81 | NPC1 (0.64) | ENPP2MGLLNPC1RAB9APTPN1 | |
| SCHEMBL6161722 | 0.80 | MGLL (0.56) | ENPP2MGLLNPC1RAB9AHDAC1 | |
| SCHEMBL3793285 | 0.79 | MGLL (0.63) | ENPP2MGLLNPC1RAB9AHDAC1 | |
| SCHEMBL27608693 | 0.78 | MGLL (0.54) | ENPP2MGLLNPC1RAB9AHDAC1 | |
| SCHEMBL5055502 | 0.77 | NPC1 (0.58) | ENPP2MGLLNPC1RAB9AEPHX1 | |
| SCHEMBL3784629 | 0.76 | HDAC1 (0.72) | ENPP2MGLLNPC1RAB9AHDAC1 | |
| SCHEMBL11627432 | 0.76 | RAB9A (0.54) | ENPP2NPC1RAB9APTPN1LMNA | |
| SCHEMBL3790841 | 0.74 | HDAC1 (0.57) | ENPP2MGLLNPC1RAB9AHDAC1 | |
| SCHEMBL6164836 | 0.74 | SUCNR1 (0.46) | ENPP2MGLLSUCNR1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1527824-A | Alkoxycarbonylamino benzoic acid or alkoxycarbonylamino tetrazolyl phenyl derilatives as IP antagonists | - | 2004-09-08 | — | — | CN | disclosed |