Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 3/20 | 0.54 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
| ▸ | MMP12 | P39900 | 1/20 | 0.45 |
| ▸ | NAAA | Q02083 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | TACR3 | P29371 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6166293 | 0.81 | PTPN1 (0.61) | MGLLENPP2NPC1RAB9AHDAC1 | |
| SCHEMBL6161722 | 0.80 | MGLL (0.56) | MGLLENPP2NPC1RAB9AHDAC1 | |
| SCHEMBL27608697 | 0.78 | ENPP2 (0.65) | MGLLENPP2NPC1RAB9AHDAC1 | |
| SCHEMBL3793285 | 0.77 | MGLL (0.63) | MGLLENPP2NPC1RAB9AHDAC1 | |
| SCHEMBL5055502 | 0.75 | NPC1 (0.58) | MGLLENPP2NPC1RAB9AEPHX1 | |
| SCHEMBL5056843 | 0.74 | CYP2C19 (0.60) | MGLLENPP2NPC1RAB9AKMT2A | |
| SCHEMBL3784629 | 0.74 | HDAC1 (0.72) | MGLLENPP2NPC1RAB9AHDAC1 | |
| SCHEMBL3495425 | 0.74 | KDM4E (0.72) | MGLLNPC1RAB9AMAOBTACR3 | |
| SCHEMBL14571741 | 0.74 | MAPT (0.58) | NPC1RAB9AHDAC1HDAC2KMT2A | |
| SCHEMBL487227 | 0.73 | ALDH1A1 (0.78) | NPC1RAB9AEPHX1MMP12NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1527824-A | Alkoxycarbonylamino benzoic acid or alkoxycarbonylamino tetrazolyl phenyl derilatives as IP antagonists | - | 2004-09-08 | — | — | CN | disclosed |