Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | CCR5 | P51681 | 1/20 | 0.38 |
| ▸ | MIF | P14174 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.36 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.34 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9803625 | 1.00 | LMNA (0.44) | LMNANOS3NOS2CCR5MIF | |
| SCHEMBL27608796 | 0.78 | HTR2A (0.41) | LMNATRPA1TAAR1CYP2D6 | |
| SCHEMBL1111815 | 0.76 | LMNA (0.45) | LMNANOS3NOS2CCR5MIF | |
| SCHEMBL5266639 | 0.76 | LMNA (0.45) | LMNANOS3NOS2CCR5TRPA1 | |
| SCHEMBL169508 | 0.75 | LMNA (0.56) | LMNANOS3NOS2CCR5MIF | |
| SCHEMBL4864892 | 0.75 | CCR5 (0.45) | LMNACCR5MIFTAAR1CYP2D6 | |
| SCHEMBL4901936 | 0.75 | CYP2C19 (0.48) | LMNACCR5MIFHKDC1TAAR1 | |
| SCHEMBL5203967 | 0.75 | LMNA (0.43) | LMNANOS3NOS2CCR5MIF | |
| SCHEMBL464510 | 0.75 | CCR5 (0.45) | LMNACCR5MIFTAAR1CYP2D6 | |
| SCHEMBL2133730 | 0.75 | CYP2C19 (0.48) | LMNACCR5MIFHKDC1TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0417167-A1 | PROCESS FOR THE SYNTHESIS OF O-SUBSTITUTED OXIME COMPOUNDS | AlliedSignal Inc. (US) | 1991-03-20 | — | — | EP | disclosed |
| WO-1989011473-A1 | PROCESS FOR THE SYNTHESIS OF O-SUBSTITUTED OXIME COMPOUNDS | ALLIED-SIGNAL INC. (US) | 1989-11-30 | — | — | WO | disclosed |
| EP-0158159-B1 | PROCESS FOR THE SYNTHESIS OF O-SUBSTITUTED OXIME COMPOUNDS AND THE CONVERSION THEREOF INTO THE CORRESPONDING HYDROXYLAMINE O-SUBSTITUTED | AlliedSignal Inc. (US) | 1988-10-05 | — | — | EP | disclosed |
| US-4614813-A | Process for the preparation of N-hydroxy organo imidate compounds | ALLIED CORPORATION (US) | 1986-09-30 | — | — | US | disclosed |
| EP-0158153-A2 | Process for the preparation of N-hydroxy organo imidate compounds | ALLIED CORPORATION (US) | 1985-10-16 | — | — | EP | disclosed |
| EP-0158159-A1 | Process for the synthesis of o-substituted oxime compounds and the conversion thereof into the corresponding hydroxylamine o-substituted | AlliedSignal Inc. (US) | 1985-10-16 | — | — | EP | disclosed |