SCHEMBL7846565

SCHEMBL7846565

O=c1c2ccccc2[nH]c2c1[nH]c1ccccc12

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.67
KDM4E B2RXH2 6/20 0.67
GLA P06280 3/20 0.67
GAA P10253 3/20 0.67
HTT P42858 3/20 0.67
LMNA P02545 2/20 0.67
HPGD P15428 1/20 0.67
ATM Q13315 1/20 0.67
SMN1; SMN2 Q16637 1/20 0.67
POLB P06746 4/20 0.58
TDP1 Q9NUW8 2/20 0.58
ABCB1 P08183 1/20 0.53
PBRM1 Q86U86 1/20 0.53
CHEK1 O14757 2/20 0.52
MEN1 O00255 4/20 0.50
KMT2A Q03164 4/20 0.50
GPR3 P46089 2/20 0.50
HSD17B10 Q99714 2/20 0.50
PARP1 P09874 2/20 0.50
PRKCA P17252 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30704463 1.00 ALDH1A1 (0.67) ALDH1A1KDM4EGLAGAAHTT
SCHEMBL5621445 0.95 ALDH1A1 (0.73) ALDH1A1KDM4EGLAGAAHTT
SCHEMBL4515369 0.85 ALDH1A1 (0.67) ALDH1A1KDM4EGLAGAAHTT
SCHEMBL14552258 0.83 ALDH1A1 (0.68) ALDH1A1KDM4EGLAGAAHTT
SCHEMBL21563828 0.82 KDM4E (0.67) ALDH1A1KDM4EGLAGAAHTT
SCHEMBL30704438 0.82 MEN1 (0.73) ALDH1A1KDM4EGLAGAAHTT
SCHEMBL27353440 0.82 MEN1 (0.73) ALDH1A1KDM4EGLAGAAHTT
Acridone SCHEMBL29360611 0.80 ALDH1A1 (1.00) ALDH1A1KDM4EGLAGAAHTT
SCHEMBL30350396 0.80 ALDH1A1 (0.90) ALDH1A1KDM4EGLAGAAHTT
Acridone SCHEMBL29641306 0.80 ALDH1A1 (1.00) ALDH1A1KDM4EGLAGAAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023249965-A1 BENZOCARBAZOLE DERIVATIVES AS INHIBITORS OF DRP1 ASHA THERAPEUTICS LLC (US) 2023-12-28 WO disclosed
EP-0710882-B1 Colour photographic material AGFA GEVAERT (BE) 2001-01-03 EP disclosed
US-5573892-A Use of Yellow couplers of the indolo [3,2-B] guinoline type in a colo ur photographic development process AGFA-GEVAERT AG (DE) 1996-11-12 US disclosed
EP-0710882-A1 New yellow couplers of indolo 3,2-b quinolin-type and their use in a colour photographic developing process Agfa-Gevaert AG (DE) 1996-05-08 EP disclosed
WO-1994018203-A1 ALKALOID COMPOUNDS EXTRACTED FROM CRYPTOLEPIS SANQUINOLENTA AND USES THEREOF HEALTHSEARCH, INC. (US) 1994-08-18 WO disclosed