Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 13/20 | 0.50 |
| ▸ | CHRM3 | P20309 | 11/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 11/20 | 0.50 |
| ▸ | CHRM5 | P08912 | 10/20 | 0.50 |
| ▸ | CHRM4 | P08173 | 9/20 | 0.50 |
| ▸ | DRD2 | P14416 | 8/20 | 0.50 |
| ▸ | DRD3 | P35462 | 8/20 | 0.50 |
| ▸ | DRD4 | P21917 | 7/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.50 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.50 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.50 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.50 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 3/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.47 |
| ▸ | HRH1 | P35367 | 2/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.44 |
| ▸ | KDM1A | O60341 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27590503 | 0.99 | CHRM1 (0.49) | CHRM1CHRM3CHRM2CHRM5CHRM4 | |
| SCHEMBL27590543 | 0.94 | CHRM1 (0.48) | CHRM1CHRM3CHRM2CHRM5CHRM4 | |
| SCHEMBL27590526 | 0.85 | KDM1A (0.55) | CHRM1CHRM3CHRM2CHRM5CHRM4 | |
| SCHEMBL27609108 | 0.78 | CHRM1 (0.50) | CHRM1CHRM3CHRM2CHRM5CHRM4 | |
| SCHEMBL27609010 | 0.78 | KDM1A (0.51) | CHRM1CHRM3CHRM2CHRM5CHRM4 | |
| SCHEMBL27590546 | 0.74 | SMN1; SMN2 (0.42) | MEN1KMT2A | |
| SCHEMBL27609019 | 0.73 | PIM1 (0.33) | HDAC6 | |
| SCHEMBL27590533 | 0.72 | HDAC3 (0.32) | KDM1AHDAC6 | |
| SCHEMBL4095785 | 0.72 | CHRM1 (0.67) | CHRM1CHRM3CHRM2CHRM5CHRM4 | |
| SCHEMBL28250648 | 0.71 | ALDH1A1 (0.38) | MEN1USP2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1561212-A | Benzimidazolone Derivatives as Muscarinic Agents | ACADIA PHARM INC (US) | 2005-01-05 | — | — | CN | disclosed |