Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 4/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.46 |
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27590526 | 0.93 | KDM1A (0.55) | KDM1ASIGMAR1ACHEMEN1KMT2A | |
| SCHEMBL27590543 | 0.83 | CHRM1 (0.48) | KDM1AMEN1KMT2ACHRM2CHRM4 | |
| SCHEMBL27609034 | 0.78 | CHRM1 (0.50) | KDM1AMEN1KMT2ACHRM2CHRM4 | |
| SCHEMBL27590503 | 0.77 | CHRM1 (0.49) | KDM1AMEN1KMT2ACHRM2CHRM4 | |
| SCHEMBL27590542 | 0.75 | MEN1 (0.40) | MEN1KMT2ACHRM2DRD2DRD3 | |
| SCHEMBL27609087 | 0.75 | GSK3B (0.34) | MEN1KMT2ASMN1; SMN2TP53 | |
| SCHEMBL27609192 | 0.74 | ACHE (0.43) | KDM1ASIGMAR1ACHECHRM2CHRM4 | |
| SCHEMBL28250648 | 0.74 | ALDH1A1 (0.38) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL27609019 | 0.71 | PIM1 (0.33) | — | |
| SCHEMBL27516784 | 0.69 | MAOA (0.41) | SMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1561212-A | Benzimidazolone Derivatives as Muscarinic Agents | ACADIA PHARM INC (US) | 2005-01-05 | — | — | CN | disclosed |