Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | HTR1A | P08908 | 2/20 | 0.36 |
| ▸ | HTR1D | P28221 | 2/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
| ▸ | HTR7 | P34969 | 2/20 | 0.36 |
| ▸ | HTR5A | P47898 | 2/20 | 0.36 |
| ▸ | TLR2 | O60603 | 1/20 | 0.36 |
| ▸ | ERN1 | O75460 | 1/20 | 0.36 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.36 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.36 |
| ▸ | MASP2 | O00187 | 1/20 | 0.35 |
| ▸ | GAPDH | P04406 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HSPA1A | P0DMV8 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27590548 | 0.79 | ALDH1A1 (0.33) | ALDH1A1CA12CA1CA2CA7 | |
| SCHEMBL27608946 | 0.77 | ERN1 (0.37) | KDM4ELMNAALDH1A1HSD17B10HPGD | |
| SCHEMBL27683810 | 0.76 | ERN1 (0.32) | KDM4EHSD17B10TDP1ERN1GAPDH | |
| SCHEMBL18885246 | 0.67 | PARP1 (0.42) | KDM4ELMNAALDH1A1HSD17B10HPGD | |
| SCHEMBL21325331 | 0.67 | KDM4E (0.35) | KDM4ELMNAALDH1A1HSD17B10TDP1 | |
| SCHEMBL7691685 | 0.67 | CYP19A1 (0.40) | KDM4EALDH1A1HTR1AHTR1DHTR2C | |
| SCHEMBL20206922 | 0.67 | HTR5A (0.37) | KDM4ELMNAALDH1A1HSD17B10TDP1 | |
| SCHEMBL20207089 | 0.67 | HTR5A (0.37) | KDM4ELMNAALDH1A1HSD17B10TDP1 | |
| SCHEMBL7691684 | 0.66 | CYP19A1 (0.40) | KDM4ELMNAALDH1A1HSD17B10TDP1 | |
| SCHEMBL27590514 | 0.66 | ALDH1A1 (0.37) | KDM4EALDH1A1ERN1HSPA1AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1561212-A | Benzimidazolone Derivatives as Muscarinic Agents | ACADIA PHARM INC (US) | 2005-01-05 | — | — | CN | disclosed |