Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | AOC3 | Q16853 | 5/20 | 0.43 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | GMNN | O75496 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11644157 | 0.82 | LMNA (0.52) | RIPK1LMNAKDM4EL3MBTL1AOC3 | |
| SCHEMBL2065739 | 0.81 | RIPK1 (0.47) | RIPK1LMNAKDM4EL3MBTL1AOC3 | |
| SCHEMBL2065087 | 0.81 | RIPK1 (0.47) | RIPK1LMNAKDM4EL3MBTL1AOC3 | |
| SCHEMBL11687409 | 0.80 | LMNA (0.54) | RIPK1LMNAKDM4EL3MBTL1AOC3 | |
| SCHEMBL28111816 | 0.80 | LMNA (0.54) | RIPK1LMNAKDM4EL3MBTL1AOC3 | |
| SCHEMBL11041488 | 0.79 | RIPK1 (0.50) | RIPK1LMNAKDM4EL3MBTL1AOC3 | |
| SCHEMBL3996513 | 0.79 | RIPK1 (0.46) | RIPK1LMNAKDM4EL3MBTL1AOC3 | |
| SCHEMBL2065088 | 0.79 | RIPK1 (0.46) | RIPK1LMNAKDM4EL3MBTL1AOC3 | |
| SCHEMBL3996526 | 0.79 | RIPK1 (0.46) | RIPK1LMNAKDM4EL3MBTL1AOC3 | |
| SCHEMBL2065740 | 0.79 | RIPK1 (0.46) | RIPK1LMNAKDM4EL3MBTL1AOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100354264-C | 5-substituted isoquinoline derivatives and drugs containing them | ASAHI KASEI PHARMA CORP (JP) | 2007-12-12 | — | — | CN | disclosed |
| CN-1668600-A | 5-substituted isoquinoline derivatives | ASAHI KASEI PHARMA CORP (JP) | 2005-09-14 | — | — | CN | disclosed |