Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MEP1B | Q16820 | 3/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA3 | P07451 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8997405 | 0.76 | ALDH1A1 (0.52) | KMT2AALDH1A1TSHRHSD17B10CA12 | |
| SCHEMBL402122 | 0.70 | KMT2A (0.59) | KMT2AALDH1A1TSHRHSD17B10CA12 | |
| SCHEMBL11581819 | 0.69 | TSHR (0.58) | KMT2AALDH1A1TSHRHSD17B10CA12 | |
| SCHEMBL1018465 | 0.69 | ALDH1A1 (0.47) | KMT2AALDH1A1TSHRHSD17B10CA12 | |
| SCHEMBL1018823 | 0.69 | ALDH1A1 (0.61) | KMT2AALDH1A1TSHRHSD17B10CA12 | |
| SCHEMBL1060743 | 0.68 | TSHR (0.56) | KMT2AALDH1A1TSHRHSD17B10CA12 | |
| SCHEMBL1060313 | 0.67 | MEP1B (0.49) | KMT2AALDH1A1TSHRMEP1BHDAC1 | |
| SCHEMBL5435259 | 0.67 | TSHR (0.55) | KMT2AALDH1A1TSHRHSD17B10CA12 | |
| SCHEMBL12169130 | 0.67 | CA1 (0.59) | KMT2AALDH1A1TSHRHSD17B10CA12 | |
| SCHEMBL29108711 | 0.67 | TSHR (0.55) | KMT2AALDH1A1TSHRHSD17B10CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1578663-A | Histone deacetylase inhibitors | METHYLGENE INC (CA) | 2005-02-09 | — | — | CN | disclosed |