Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FTO | Q9C0B1 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | PDE2A | O00408 | 2/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | IL2 | P60568 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL266467 | 0.82 | PTPN1 (0.47) | FTOPTPN1MEN1KMT2AHTT | |
| SCHEMBL2056340 | 0.78 | FTO (0.52) | FTOPTPN1MEN1KMT2AHTT | |
| SCHEMBL6009742 | 0.78 | MEN1 (0.45) | FTOPTPN1MEN1KMT2AHTT | |
| SCHEMBL4030956 | 0.78 | PTPN1 (0.50) | FTOPTPN1MEN1KMT2AHTT | |
| SCHEMBL19785385 | 0.78 | PDE2A (0.47) | MEN1KMT2AKDM1APDE2ACTSS | |
| SCHEMBL30370342 | 0.77 | MEN1 (0.57) | MEN1KMT2AHTTSMN1; SMN2KDM4E | |
| SCHEMBL3063301 | 0.77 | MEN1 (0.54) | FTOPTPN1MEN1KMT2AHTT | |
| SCHEMBL4946316 | 0.77 | MEN1 (0.57) | MEN1KMT2AHTTSMN1; SMN2KDM4E | |
| SCHEMBL13078465 | 0.76 | MEN1 (0.56) | PTPN1MEN1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL13718757 | 0.75 | FTO (0.49) | FTOPTPN1MEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1549714-A | Aminoisoxazole derivatives active as kinase inhibitors | — | 2004-11-24 | — | — | CN | disclosed |