Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.40 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.39 |
| ▸ | BIRC5 | O15392 | 2/20 | 0.37 |
| ▸ | PDE2A | O00408 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | IL2 | P60568 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27609990 | 0.78 | FTO (0.45) | MEN1KMT2AFTOHTTSMN1; SMN2 | |
| SCHEMBL266467 | 0.77 | PTPN1 (0.47) | MEN1KMT2AFTOHTTSMN1; SMN2 | |
| SCHEMBL4030956 | 0.77 | PTPN1 (0.50) | MEN1KMT2AFTOHTTSMN1; SMN2 | |
| SCHEMBL30370342 | 0.75 | MEN1 (0.57) | MEN1KMT2AHTTSMN1; SMN2KDM4E | |
| SCHEMBL3063301 | 0.75 | MEN1 (0.54) | MEN1KMT2AFTOHTTSMN1; SMN2 | |
| SCHEMBL4946316 | 0.75 | MEN1 (0.57) | MEN1KMT2AHTTSMN1; SMN2KDM4E | |
| SCHEMBL2318440 | 0.74 | CYP1A1 (0.42) | — | |
| SCHEMBL13078465 | 0.74 | MEN1 (0.56) | MEN1KMT2AHTTSMN1; SMN2PTPN1 | |
| SCHEMBL2056340 | 0.73 | FTO (0.52) | MEN1KMT2AFTOHTTSMN1; SMN2 | |
| SCHEMBL19785385 | 0.73 | PDE2A (0.47) | MEN1KMT2ABIRC5PDE2ACTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1697335-A1 | FURANCARBONYLGUANIDINE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2006-09-06 | — | — | EP | disclosed |
| WO-2005063727-A1 | FURANCARBONYLGUANIDINE DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2005-07-14 | — | — | WO | disclosed |