Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R2 | Q9NPC1 | 17/20 | 0.52 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.46 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3814853 | 0.94 | LTB4R2 (0.45) | LTB4R2PTGDR2 | |
| SCHEMBL3807189 | 0.90 | PTGDR2 (0.50) | LTB4R2PTGDR2 | |
| SCHEMBL28753492 | 0.90 | LTB4R2 (0.54) | LTB4R2AGTR1 | |
| SCHEMBL27610388 | 0.88 | LTB4R2 (0.54) | LTB4R2AGTR1 | |
| SCHEMBL27610442 | 0.87 | LTB4R2 (0.55) | LTB4R2AGTR1 | |
| SCHEMBL3811516 | 0.86 | MTOR (0.41) | LTB4R2PTGDR2 | |
| SCHEMBL2157665 | 0.85 | LTB4R2 (0.44) | LTB4R2PTGDR2 | |
| SCHEMBL2244801 | 0.85 | PTGES (0.45) | LTB4R2 | |
| SCHEMBL3807453 | 0.83 | MLYCD (0.43) | LTB4R2PTGDR2 | |
| SCHEMBL27610399 | 0.82 | LTB4R2 (0.52) | LTB4R2PTGDR2AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100509797-C | Thiophene derivatives as antiviral agents against flavivirus infections | VIRUS CHEM PHARMA INC (CA) | 2009-07-08 | — | — | CN | claimed |
| CN-1602308-A | Thiophene derivatives as antiviral agents against flavivirus infections | VIRUS CHEM PHARMA INC (CA) | 2005-03-30 | — | — | CN | claimed |
| CN-101624391-A | Thiophene derivatives as antiviral agents for flavivirus infection | VIROCHEM PHARMA INC | 2010-01-13 | — | — | CN | disclosed |
| CN-100509797-C | Thiophene derivatives as antiviral agents against flavivirus infections | VIRUS CHEM PHARMA INC (CA) | 2009-07-08 | — | — | CN | disclosed |
| CN-1602308-A | Thiophene derivatives as antiviral agents against flavivirus infections | VIRUS CHEM PHARMA INC (CA) | 2005-03-30 | — | — | CN | disclosed |