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Arginine

Arginine

SCHEMBL27611401

CC(C)C[C@H](N)C(=O)O.CC[C@H](C)[C@H](N)C(=O)O.CSCC[C@H](N)C(=O)O.C[C@H](N)C(=O)O.N=C(N)NCCC[C@H](N)C(=O)O.NC(=O)CC[C@H](N)C(=O)O.NC(=O)C[C@H](N)C(=O)O.NCC(=O)O.NCCCC[C@H](N)C(=O)O.N[C@@H](CC(=O)O)C(=O)O.N[C@@H](CCC(=O)O)C(=O)O.N[C@@H](CS)C(=O)O.N[C@@H](Cc1c[nH]cn1)C(=O)O

nearest known ligand 0.36

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACE

The experimentally established mechanism targets of Arginine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ PTH1R Q03431 8/20 0.36
▸ CALCR P30988 3/20 0.34
▸ VIPR2 P41587 5/20 0.34
▸ VIPR1 P32241 3/20 0.34
▸ APLNR P35414 1/20 0.34
▸ GLP1R P43220 1/20 0.34
▸ KEAP1 Q14145 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Arginine SCHEMBL6481630 0.96 GLP1R (0.35) VIPR2VIPR1GLP1R
Arginine SCHEMBL27629650 0.94 GLP1R (0.34) GLP1R
Arginine SCHEMBL27640159 0.92 GLP1R (0.33) GLP1R
Arginine SCHEMBL27495388 0.91 PTH1R (0.38) PTH1RVIPR2VIPR1APLNRGLP1R
Cystine SCHEMBL27709554 0.89 GLP1R (0.32) GLP1R
Cystine SCHEMBL9697229 0.88 CALCR (0.37) PTH1RCALCRAPLNRKEAP1
Arginine SCHEMBL28484320 0.88 VIPR2 (0.36) VIPR2VIPR1GLP1R
D-Histidine SCHEMBL27900898 0.88 BACE1 (0.33) CALCR
Arginine SCHEMBL28894222 0.87 APLNR (0.36) PTH1RCALCRAPLNRGLP1R
Arginine SCHEMBL28894087 0.87 APLNR (0.36) PTH1RCALCRAPLNRGLP1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1678755-A Compositions and methods for determining the susceptibility of a pathogenic virus to protease inhibitors VIROLOGIC INC (US) 2005-10-05 — — CN disclosed