Cystine

Cystine

SCHEMBL27709554

CC[C@H](C)[C@H](N)C(=O)O.C[C@H](N)C(=O)O.N=C(N)NCCC[C@H](N)C(=O)O.NC(=O)CC[C@H](N)C(=O)O.NC(=O)C[C@H](N)C(=O)O.NCC(=O)O.N[C@@H](CC(=O)O)C(=O)O.N[C@@H](CCC(=O)O)C(=O)O.N[C@@H](CS)C(=O)O.N[C@@H](CSSC[C@H](N)C(=O)O)C(=O)O.N[C@@H](Cc1c[nH]cn1)C(=O)O

nearest known ligand 0.32

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACE

The experimentally established mechanism targets of Cystine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GLP1R P43220 9/20 0.32
KLK7 P49862 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Arginine SCHEMBL27640159 0.96 GLP1R (0.33) GLP1RKLK7
Arginine SCHEMBL27629650 0.94 GLP1R (0.34) GLP1R
Cystine SCHEMBL10538206 0.93 GLP1R (0.33) GLP1R
Arginine SCHEMBL6481630 0.92 GLP1R (0.35) GLP1R
Arginine SCHEMBL6435765 0.91 GLP1R (0.32) GLP1RKLK7
Arginine SCHEMBL27611401 0.89 PTH1R (0.36) GLP1R
Cystine SCHEMBL9667228 0.86 CALCR (0.32) GLP1R
Cystine SCHEMBL9667231 0.86 CALCR (0.32) GLP1R
Cystine SCHEMBL9697229 0.84 CALCR (0.37)
Arginine SCHEMBL8995772 0.84 NPY4R (0.32) GLP1RKLK7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101237855-A Lipid construct for delivery of interferon to a mammal SDG INC (US) 2008-08-06 CN disclosed