Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPN1 | P15169 | 1/20 | 0.41 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 5/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.37 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | HPGDS | O60760 | 1/20 | 0.33 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.33 |
| ▸ | DDX3X | O00571 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27389052 | 0.82 | CYP1A2 (0.43) | L3MBTL1ALOX5 | |
| SCHEMBL28025968 | 0.79 | MEN1 (0.48) | L3MBTL1ALDH1A1ALOX5 | |
| SCHEMBL8953959 | 0.78 | CYP3A4 (0.37) | CPN1CPB2ADRB2ADRB3ADRB1 | |
| SCHEMBL1067891 | 0.76 | CPN1 (0.47) | CPN1CPB2ADRB2ADRB3ADRB1 | |
| SCHEMBL28140608 | 0.75 | CYP17A1 (0.40) | L3MBTL1ALDH1A1 | |
| SCHEMBL27493803 | 0.74 | ESR1 (0.41) | ALDH1A1CA1CA2CA9 | |
| SCHEMBL5796124 | 0.74 | APP (0.47) | CPN1CPB2ADRB2ADRB3ADRB1 | |
| SCHEMBL27647919 | 0.73 | ALOX5 (0.46) | ALDH1A1ALOX5 | |
| SCHEMBL27510737 | 0.73 | ACACB (0.36) | ALOX5 | |
| SCHEMBL7336123 | 0.72 | CPN1 (0.43) | CPN1CPB2ADRB2ADRB3ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100348196-C | Benzotriaza * as gastrin and cholecystokinin receptor ligands | BLACK JAMES FOUNDATION (GB) | 2007-11-14 | — | — | CN | disclosed |
| CN-1585643-A | Benzotriazepines as gastrin and cholecystokinin receptor ligands | BLACK JAMES FOUNDATION (GB) | 2005-02-23 | — | — | CN | disclosed |