Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.42 |
| ▸ | CPN1 | P15169 | 1/20 | 0.42 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.36 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7336123 | 0.86 | CPN1 (0.43) | ADRB2ADRB1ADRB3CPN1CPB2 | |
| SCHEMBL27493979 | 0.85 | ADRB1 (0.40) | ADRB2ADRB1ADRB3CPN1CPB2 | |
| SCHEMBL7210714 | 0.84 | CPN1 (0.42) | ADRB2ADRB1ADRB3CPN1CPB2 | |
| SCHEMBL27494783 | 0.84 | ADRB2 (0.40) | APPADRB2ADRB1ADRB3CPN1 | |
| SCHEMBL5213655 | 0.83 | APP (0.48) | APPPTGS1PTGS2ADRB2ADRB1 | |
| SCHEMBL28006901 | 0.82 | CPN1 (0.48) | PTGS1ADRB2ADRB1ADRB3CPN1 | |
| SCHEMBL31478060 | 0.82 | PTGS1 (0.60) | PTGS1PTGS2ADRB2ADRB1ADRB3 | |
| SCHEMBL3402993 | 0.82 | PTGS1 (0.60) | PTGS1PTGS2ADRB2ADRB1ADRB3 | |
| SCHEMBL1000053 | 0.82 | PTGS1 (0.45) | PTGS1PTGS2ADRB2ADRB1ADRB3 | |
| SCHEMBL7461910 | 0.82 | CPN1 (0.47) | ADRB2ADRB1ADRB3CPN1CPB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006051312-A1 | GASTRIN AND CHOLECYSTOKININ RECEPTOR LIGANDS | JAMES BLACK FOUNDATION LIMITED (GB) | 2006-05-18 | — | — | WO | disclosed |
| CN-1178523-A | Aminophenol derivatives | DIICHI PHARMACEUTICAL CO LTD (JP) | 1998-04-08 | — | — | CN | disclosed |