Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ACP3 | P15309 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27611549 | 0.79 | CPN1 (0.41) | L3MBTL1ALDH1A1ALOX5 | |
| Dinitrophenylene SCHEMBL28255199 | 0.79 | TSHR (0.55) | MEN1KMT2ATSHRALDH1A1LMNA | |
| SCHEMBL1067934 | 0.78 | ACP3 (0.50) | MEN1KMT2AL3MBTL1HPGDACP3 | |
| SCHEMBL10573663 | 0.78 | TSHR (0.50) | MEN1KMT2AL3MBTL1HPGDACP3 | |
| SCHEMBL27919083 | 0.77 | ALDH1A1 (0.49) | MEN1KMT2AL3MBTL1HPGDACP3 | |
| SCHEMBL27389052 | 0.77 | CYP1A2 (0.43) | KMT2AL3MBTL1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL30428765 | 0.76 | TSHR (0.54) | MEN1KMT2AL3MBTL1HPGDACP3 | |
| SCHEMBL10763187 | 0.76 | TSHR (0.54) | MEN1KMT2AL3MBTL1HPGDACP3 | |
| SCHEMBL11092415 | 0.76 | MAPT (0.48) | MEN1KMT2AL3MBTL1HPGDACP3 | |
| Hydrochloric Acid SCHEMBL27290579 | 0.75 | L3MBTL1 (0.55) | MEN1KMT2AL3MBTL1HPGDACP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104755461-A | 6-aminoindole derivatives as TRP channel antagonists | HOFFMANN LA ROCHE | 2015-07-01 | — | — | CN | disclosed |