Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 4/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.33 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.33 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.33 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.33 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.32 |
| ▸ | BAD | Q92934 | 1/20 | 0.32 |
| ▸ | GNG2 | P59768 | 1/20 | 0.32 |
| ▸ | GNB1 | P62873 | 1/20 | 0.32 |
| ▸ | NQO1 | P15559 | 1/20 | 0.31 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
| ▸ | STAT3 | P40763 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27781003 | 0.84 | — | — | |
| SCHEMBL28024035 | 0.79 | CES1 (0.37) | CES1KIF11GRIA1GRIA2GRIA3 | |
| SCHEMBL27697057 | 0.79 | — | — | |
| SCHEMBL27994256 | 0.79 | — | — | |
| SCHEMBL27855741 | 0.77 | KIF11 (0.33) | CES1KIF11BCL2L1BADSTAT3 | |
| SCHEMBL27838062 | 0.77 | CES1 (0.31) | CES1KIF11STAT3 | |
| SCHEMBL27883165 | 0.74 | KIF11 (0.31) | CES1KIF11GNG2GNB1 | |
| SCHEMBL27837968 | 0.74 | KDM4E (0.31) | — | |
| SCHEMBL28751592 | 0.74 | HPRT1 (0.37) | KIF11BCL2L1BADNQO1 | |
| SCHEMBL8666055 | 0.73 | ALDH1A1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103889224-B | ANTIBACTERIAL COMPOUNDS AND METHODS FOR USE | PTC医疗公司 | 2017-05-24 | — | — | CN | claimed |
| CN-107925004-A | Organic molecule for organic electro-optic device | 西诺拉股份有限公司 | 2018-04-17 | — | — | CN | disclosed |
| CN-103450218-B | As the indoles three also ring derivatives of CRTH2 receptor antagonist | SHANDONG HENRY MEDICAL SCIENCE AND TECHNOLOGY CO., LTD. (CN) | 2015-12-23 | — | — | CN | disclosed |
| CN-102791689-B | 3- (heteroaryl-amino) -1,2,3, 4-tetrahydro-9H-carbazole derivatives and their use as prostaglandin D2 receptor modulators | ACTELION PHARMACEUTICALS LTD. (CH) | 2014-10-29 | — | — | CN | disclosed |
| CN-101687799-B | Novel vanilloid receptor ligands and the use thereof for the production of pharmaceuticals | GRUENENTHAL GMBH | 2014-07-23 | — | — | CN | disclosed |
| CN-103450218-A | Indole tricyclic derivative as CRTH2 receptor antagonist | SHANDONG HENGLI MEDICAL TECHNOLOGY CO LTD | 2013-12-18 | — | — | CN | disclosed |
| CN-102791689-A | 3- (heteroaryl-amino) -1,2,3, 4-tetrahydro-9H-carbazole derivatives and their use as prostaglandin D2 receptor modulators | ACTELION PHARMACEUTICALS LTD | 2012-11-21 | — | — | CN | disclosed |
| CN-101687799-A | Novel vanilloid receptor ligands and the use thereof for the production of pharmaceuticals | GRUENENTHAL GMBH | 2010-03-31 | — | — | CN | disclosed |
| CN-100500654-C | Tetrahydrocarbazole derivatives as ligands for G-protein coupled receptors (GPCRs) | ZENTARIS AG (DE) | 2009-06-17 | — | — | CN | disclosed |
| CN-101120002-A | Cycloalkyl-fused indole, benzothiophene, benzofuran and indene derivatives | WYETH CORP (US) | 2008-02-06 | — | — | CN | disclosed |
| CN-1599720-A | Tetrahydrocarbazole derivatives as ligands for G-protein coupled receptors (GPCRs) | ZENTARIS AG (DE) | 2005-03-23 | — | — | CN | disclosed |