Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4001655 | 0.82 | MAPT (0.64) | GRM5MAPTMEN1KMT2ACHRNB2 | |
| SCHEMBL8288267 | 0.70 | GRM5 (0.61) | GRM5MAPTMEN1KMT2ACHRNB2 | |
| SCHEMBL1985000 | 0.69 | CHRNB2 (0.65) | GRM5MAPTMEN1KMT2ACHRNB2 | |
| SCHEMBL31037156 | 0.69 | CHRNB2 (0.65) | GRM5MAPTMEN1KMT2ACHRNB2 | |
| SCHEMBL15498199 | 0.69 | CHRNB2 (0.73) | MAPTMEN1KMT2ACHRNB2CHRNA4 | |
| SCHEMBL16178929 | 0.69 | CHRNB2 (0.64) | GRM5MAPTCHRNB2CHRNA4SMN1; SMN2 | |
| SCHEMBL12653007 | 0.68 | NPC1 (0.70) | GRM5MAPTMEN1KMT2ACHRNB2 | |
| Ammonia Solution, Strong SCHEMBL3031537 | 0.68 | CHRNB2 (0.63) | GRM5MAPTMEN1KMT2ACHRNB2 | |
| Hydrochloric Acid SCHEMBL10551173 | 0.68 | CHRNB2 (0.62) | GRM5MAPTCHRNB2CHRNA4SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL10551171 | 0.68 | CHRNB2 (0.62) | GRM5MAPTCHRNB2CHRNA4SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1678321-A | Methods of treating or preventing autoimmune diseases with 2, 4-pyrimidinediamine compounds | RIGEL PHARMACEUTICALS INC (US) | 2005-10-05 | — | — | CN | disclosed |