Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.56 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.52 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.45 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5779338 | 0.86 | LMNA (0.56) | GRM5LMNAMAPTPKMRAB9A | |
| SCHEMBL6068789 | 0.82 | LMNA (0.53) | GRM5LMNAMAPTPKMRAB9A | |
| SCHEMBL14988594 | 0.81 | TLR4 (0.63) | LMNAMAPTPKMRAB9ASMN1; SMN2 | |
| SCHEMBL9721944 | 0.81 | LMNA (0.56) | GRM5LMNAMAPTPKMRAB9A | |
| SCHEMBL1015664 | 0.80 | MAPT (0.53) | LMNAMAPTRAB9ASMN1; SMN2MEN1 | |
| SCHEMBL5779125 | 0.79 | CYSLTR1 (0.62) | LMNAMAPTSMN1; SMN2RXFP1 | |
| SCHEMBL9795659 | 0.76 | MAOB (0.62) | MAPTRAB9ACHRNB2CHRNA4MEN1 | |
| SCHEMBL8170687 | 0.76 | MAPT (0.51) | GRM5LMNAMAPTPKMRAB9A | |
| SCHEMBL28057927 | 0.76 | MAPT (0.53) | GRM5LMNAMAPTPKMRAB9A | |
| SCHEMBL8288269 | 0.76 | MAOB (0.56) | LMNAMAPTRAB9ASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005044265-A1 | ALKYNES III | ASTRAZENECA AB (SE) | 2005-05-19 | — | — | WO | disclosed |