Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.51 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.51 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.51 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.46 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | ADH5 | P11766 | 1/20 | 0.43 |
| ▸ | WNT3A | P56704 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7434598 | 0.76 | TBXAS1 (0.68) | ENPP2MKNK1MKNK2TBXAS1LMNA | |
| SCHEMBL10756712 | 0.76 | CYP3A4 (0.56) | ENPP2MKNK1MKNK2TBXAS1LMNA | |
| SCHEMBL857216 | 0.75 | ENPP2 (0.63) | ENPP2MKNK1MKNK2TBXAS1LMNA | |
| SCHEMBL22486535 | 0.75 | LMNA (0.58) | ENPP2MKNK1MKNK2TBXAS1LMNA | |
| SCHEMBL27613141 | 0.75 | ENPP2 (0.54) | ENPP2MKNK1MKNK2TBXAS1LMNA | |
| SCHEMBL7403488 | 0.75 | CYP3A4 (0.64) | ENPP2MKNK1MKNK2TBXAS1LMNA | |
| SCHEMBL8401615 | 0.75 | ENPP2 (0.54) | ENPP2MKNK1MKNK2TBXAS1LMNA | |
| SCHEMBL21791731 | 0.75 | LMNA (0.62) | ENPP2MKNK1MKNK2TBXAS1LMNA | |
| SCHEMBL2532397 | 0.74 | LMNA (0.78) | ENPP2MKNK1MKNK2LMNAMAPT | |
| SCHEMBL6850622 | 0.73 | MAPT (0.53) | ENPP2MKNK1MKNK2TBXAS1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1585775-A | 6-O-acyl ketolide derivatives of erythromycine useful as antibacterials | ORTHO MCNEIL PHARM INC (US) | 2005-02-23 | — | — | CN | disclosed |