Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WNT3A | P56704 | 14/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.37 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
| ▸ | EP300 | Q09472 | 2/20 | 0.35 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.33 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27613083 | 0.80 | CYP1A2 (0.42) | WNT3A | |
| SCHEMBL6215593 | 0.75 | MKNK1 (0.50) | WNT3AHDAC4DHODHEP300PRMT5 | |
| SCHEMBL27612787 | 0.75 | HDAC4 (0.39) | WNT3AHDAC4DHODHEP300PRMT5 | |
| SCHEMBL27594249 | 0.74 | ADRB2 (0.50) | WNT3AHDAC4 | |
| SCHEMBL27613089 | 0.74 | MKNK1 (0.58) | WNT3A | |
| SCHEMBL27612999 | 0.74 | CYP17A1 (0.42) | WNT3A | |
| SCHEMBL6877341 | 0.73 | HDAC4 (0.37) | WNT3AHDAC4DHODHEP300PRMT5 | |
| SCHEMBL6877337 | 0.73 | HDAC4 (0.37) | WNT3AHDAC4DHODHEP300PRMT5 | |
| SCHEMBL6877331 | 0.73 | HDAC4 (0.37) | WNT3AHDAC4DHODHEP300PRMT5 | |
| SCHEMBL27612894 | 0.73 | CYP2D6 (0.43) | WNT3AHDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1585775-A | 6-O-acyl ketolide derivatives of erythromycine useful as antibacterials | ORTHO MCNEIL PHARM INC (US) | 2005-02-23 | — | — | CN | disclosed |