Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | MMP1 | P03956 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | MMP13 | P45452 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4831153 | 0.82 | RAB9A (0.71) | MMP1MMP13RAB9AGAAALDH1A1 | |
| SCHEMBL1977126 | 0.81 | HDAC1 (0.72) | HDAC1HDAC6HDAC8MMP1MMP2 | |
| SCHEMBL3327057 | 0.80 | LMNA (0.65) | HDAC1HDAC6HDAC8MMP1MMP2 | |
| SCHEMBL2296626 | 0.78 | RAB9A (0.66) | HDAC1HDAC6HDAC8RAB9AGAA | |
| SCHEMBL4834106 | 0.78 | ALDH1A1 (0.50) | HDAC1HDAC6RAB9AGAAALDH1A1 | |
| SCHEMBL4831350 | 0.76 | HDAC1 (0.50) | HDAC1HDAC6RAB9AGAAALDH1A1 | |
| SCHEMBL1836543 | 0.76 | POLB (0.46) | HDAC1HDAC6RAB9AGAAALDH1A1 | |
| SCHEMBL1979349 | 0.76 | LMNA (0.70) | HDAC1HDAC6HDAC8MMP1MMP2 | |
| SCHEMBL1658832 | 0.76 | HDAC1 (0.51) | HDAC1HDAC6HDAC8MMP1MMP2 | |
| SCHEMBL10668105 | 0.74 | POLB (0.59) | RAB9AGAAALDH1A1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1731994-A | Prophylactic and therapeutic agent for neuropathy | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2006-02-08 | — | — | CN | disclosed |