SCHEMBL8779784

SCHEMBL8779784

CC(C)(C)OC(=O)N(N)C(=O)Oc1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 4/20 0.47
ATM Q13315 2/20 0.47
TDP1 Q9NUW8 2/20 0.47
RAB9A P51151 3/20 0.44
KMT2A Q03164 3/20 0.44
NPSR1 Q6W5P4 2/20 0.44
MEN1 O00255 2/20 0.44
ALDH1A1 P00352 1/20 0.41
PKM P14618 1/20 0.41
ELANE P08246 2/20 0.40
NPC1 O15118 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
MAPT P10636 1/20 0.38
NPY5R Q15761 1/20 0.38
PTGES O14684 1/20 0.37
MMP13 P45452 1/20 0.37
NSD2 O96028 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4514786 0.78 ALDH1A1 (0.43) L3MBTL1TDP1KMT2AMEN1ALDH1A1
SCHEMBL1706932 0.78 HDAC6 (0.38) SMN1; SMN2
SCHEMBL25725295 0.78 GBA1 (0.46) L3MBTL1ATMTDP1RAB9AKMT2A
SCHEMBL27613428 0.77 L3MBTL1 (0.52) L3MBTL1ATMTDP1RAB9AKMT2A
SCHEMBL6648512 0.76 ALDH1A1 (0.49) L3MBTL1TDP1KMT2AALDH1A1SMN1; SMN2
SCHEMBL15235847 0.75 L3MBTL1 (0.42) L3MBTL1ATMTDP1RAB9AKMT2A
SCHEMBL11029662 0.74 TDP1 (0.57) L3MBTL1ATMTDP1RAB9AKMT2A
SCHEMBL82142 0.74 ELANE (0.67) L3MBTL1ATMTDP1KMT2AALDH1A1
SCHEMBL11771781 0.74 ELANE (0.67) L3MBTL1ATMTDP1KMT2AALDH1A1
SCHEMBL2354804 0.74 L3MBTL1 (0.43) L3MBTL1ATMTDP1RAB9AKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0525197-B1 3-BENZYLIDENE-1-CARBAMOYL-2-PYRROLIDONE ANALOGS SHIONOGI & CO (JP) 1997-08-27 EP disclosed