Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
| ▸ | NOS3 | P29474 | 3/20 | 0.34 |
| ▸ | NOS2 | P35228 | 3/20 | 0.34 |
| ▸ | NOS1 | P29475 | 2/20 | 0.34 |
| ▸ | GABRP | O00591 | 1/20 | 0.31 |
| ▸ | GABRD | O14764 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.31 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.31 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.31 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.31 |
| ▸ | GABRE | P78334 | 1/20 | 0.31 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.31 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.31 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL34472956 | 0.84 | PDE3B (0.39) | PDE3BPDE3ANOS3NOS2NOS1 | |
| SCHEMBL1131513 | 0.84 | PDE3B (0.39) | PDE3BPDE3ANOS3NOS2NOS1 | |
| SCHEMBL6449401 | 0.83 | PDE3B (0.35) | PDE3BPDE3A | |
| Ammonia Solution, Strong SCHEMBL28980458 | 0.81 | PDE3B (0.38) | PDE3BPDE3ANOS3NOS2NOS1 | |
| Formamide SCHEMBL10696206 | 0.79 | ALDH1A1 (0.35) | PDE3BPDE3AGABRA1GABRB2 | |
| SCHEMBL7497070 | 0.77 | PDE3B (0.33) | PDE3BPDE3ANOS3NOS2NOS1 | |
| SCHEMBL3931270 | 0.76 | PDE3B (0.34) | PDE3BPDE3A | |
| SCHEMBL29954185 | 0.76 | PDE3B (0.34) | PDE3BPDE3A | |
| Formamide SCHEMBL29265662 | 0.76 | PDE3B (0.36) | PDE3BPDE3ANOS3NOS2NOS1 | |
| Formamide SCHEMBL27824881 | 0.75 | NOS3 (0.37) | PDE3BPDE3ANOS3NOS2NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1726042-A | Benzo[d]azepine derivatives for the treatment of neurological disorders | GLAXO GROUP LTD (GB) | 2006-01-25 | — | — | CN | disclosed |