Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 4/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | EGFR | P00533 | 1/20 | 0.52 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.49 |
| ▸ | NAMPT | P43490 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Toluene SCHEMBL28036643 | 1.00 | NAAA (0.59) | NAAAL3MBTL1EPHX1HTTALDH1A1 | |
| Toluene SCHEMBL27499889 | 0.93 | TSHR (0.54) | NAAAL3MBTL1EPHX1HTTALDH1A1 | |
| Toluene SCHEMBL28076346 | 0.92 | TSHR (0.53) | NAAAL3MBTL1EPHX1HTTALDH1A1 | |
| M-Xylene SCHEMBL8398536 | 0.89 | L3MBTL1 (0.53) | NAAAL3MBTL1EPHX1HTTALDH1A1 | |
| Toluene SCHEMBL30957356 | 0.88 | NAAA (0.65) | NAAAL3MBTL1EPHX1HTTALDH1A1 | |
| Toluene SCHEMBL30957366 | 0.88 | NAAA (0.65) | NAAAL3MBTL1EPHX1HTTALDH1A1 | |
| Toluene SCHEMBL30957374 | 0.88 | NAAA (0.65) | NAAAL3MBTL1EPHX1HTTALDH1A1 | |
| Toluene SCHEMBL30957355 | 0.88 | NAAA (0.65) | NAAAL3MBTL1EPHX1HTTALDH1A1 | |
| Toluene SCHEMBL30957338 | 0.88 | NAAA (0.65) | NAAAL3MBTL1EPHX1HTTALDH1A1 | |
| Toluene SCHEMBL30957319 | 0.88 | NAAA (0.65) | NAAAL3MBTL1EPHX1HTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101537182-A | Combination comprising an HMG CoA reductase inhibitor and an insulin secretor enhancer or an insulin sensitizer | NOVARTIS AG (CH) | 2009-09-23 | — | — | CN | claimed |
| CN-101355949-A | Combination of triazine derivatives and insulin secretion enhancers | MERCK PATENT GMBH (DE) | 2009-01-28 | — | — | CN | claimed |
| CN-1642559-A | Combination comprising an HMG CoA reductase inhibitor and an insulin secretion enhancer or insulin sensitizer | NOVARTIS AG (CH) | 2005-07-20 | — | — | CN | claimed |
| CN-102188705-A | Medicament composition containing bis cyclooctane derivatives | LIYAN WANG | 2011-09-21 | — | — | CN | disclosed |
| CN-101822836-A | Medicine composition containing allisartan isoproxil | LIYAN WANG | 2010-09-08 | — | — | CN | disclosed |
| CN-101822837-A | Medicine composition containing allisartan isoproxil salts | LIYAN WANG | 2010-09-08 | — | — | CN | disclosed |
| CN-101822667-A | Medicine composition containing imidazole-5-carboxylic acid derivatives | LIYAN WANG | 2010-09-08 | — | — | CN | disclosed |
| CN-101810859-A | Medical composition containing aniline derivative | LIYAN WANG | 2010-08-25 | — | — | CN | disclosed |
| CN-101732718-A | Pharmaceutical composition containing NCX inhibitors | LIYAN WANG | 2010-06-16 | — | — | CN | disclosed |
| CN-101537182-A | Combination comprising an HMG CoA reductase inhibitor and an insulin secretor enhancer or an insulin sensitizer | NOVARTIS AG (CH) | 2009-09-23 | — | — | CN | disclosed |
| CN-101355949-A | Combination of triazine derivatives and insulin secretion enhancers | MERCK PATENT GMBH (DE) | 2009-01-28 | — | — | CN | disclosed |
| CN-1642559-A | Combination comprising an HMG CoA reductase inhibitor and an insulin secretion enhancer or insulin sensitizer | NOVARTIS AG (CH) | 2005-07-20 | — | — | CN | disclosed |