Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 5/20 | 0.51 |
| ▸ | NAAA | Q02083 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | ALB | P02768 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | FBP1 | P09467 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Toluene SCHEMBL27499889 | 0.98 | TSHR (0.54) | TSHRHTTHPGDNAAAL3MBTL1 | |
| Toluene SCHEMBL27615145 | 0.92 | NAAA (0.59) | TSHRHTTHPGDNAAAL3MBTL1 | |
| Toluene SCHEMBL28036643 | 0.92 | NAAA (0.59) | TSHRHTTHPGDNAAAL3MBTL1 | |
| Benzene SCHEMBL28109469 | 0.88 | HTT (0.50) | TSHRHTTHPGDNAAAALDH1A1 | |
| Toluene SCHEMBL28333239 | 0.86 | HTT (0.59) | TSHRHTTHPGDNAAAL3MBTL1 | |
| P-Cresol SCHEMBL27759325 | 0.85 | HPGD (0.54) | TSHRHTTHPGDNAAAL3MBTL1 | |
| Orthocresol SCHEMBL27787642 | 0.83 | NAAA (0.49) | TSHRHTTHPGDNAAAALDH1A1 | |
| Hydrogen Sulfide SCHEMBL27785367 | 0.82 | — | — | |
| Toluene SCHEMBL30957363 | 0.81 | NAAA (0.62) | TSHRHTTHPGDNAAAL3MBTL1 | |
| M-Xylene SCHEMBL8398536 | 0.81 | L3MBTL1 (0.53) | HTTNAAAL3MBTL1ALDH1A1EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109640993-A | Comprising amodiaquine and antidiabetic medicine as effective component for preventing or treating the pharmaceutical compositions of diabetes | 诺麦塔制药有限公司 | 2019-04-16 | — | — | CN | claimed |
| CN-107857823-A | The extracting method of Auricularia polysaccharide | 金华市艾力生物科技有限公司 | 2018-03-30 | — | — | CN | claimed |
| CN-107106873-A | ACC inhibitor combined therapies for treating non-alcoholic fatty liver disease | 吉利德阿波罗公司 | 2017-08-29 | — | — | CN | claimed |
| CN-110514753-A | A method of utilizing the illegal additive in polynary multi-dimensional chromatograph finger-print screening hypoglycemic health-care product | UNIV GUANGDONG PHARM | 2019-11-29 | — | — | CN | disclosed |
| CN-110494141-A | Pharmaceutical composition containing substituted polycyclic Pyridione derivatives and its prodrug | SHIONOGI & CO | 2019-11-22 | — | — | CN | disclosed |
| CN-110461337-A | Medical composition and its use with bile acid derivative and microorganism group | INTERCEPT PHARMACEUTICALS INC | 2019-11-15 | — | — | CN | disclosed |
| CN-110382503-A | Process for preparing ACC inhibitors and solid forms thereof | 吉利德科学公司 | 2019-10-25 | — | — | CN | disclosed |
| CN-110279852-A | Stabilized pharmaceutical formulations of insulin analogues and/or insulin derivatives | 赛诺菲 | 2019-09-27 | — | — | CN | disclosed |
| CN-110072850-A | 3-sulfonyl-5-aminopyridine-2, 4-diol APJ agonists | 百时美施贵宝公司 | 2019-07-30 | — | — | CN | disclosed |
| CN-110072862-A | Bicyclic nitrogen-containing heterocyclic derivative and pharmaceutical composition containing the same | 盐野义制药株式会社 | 2019-07-30 | — | — | CN | disclosed |
| CN-110049757-A | Rapidly disintegrating pharmaceutical composition | 辉凌公司 | 2019-07-23 | — | — | CN | disclosed |
| CN-104640856-B | Carbazole-containing sulfonamides as cryptochrome modulators | 复位治疗公司 | 2017-09-15 | — | — | CN | disclosed |
| CN-102149280-B | Deuterated benzylbenzene derivatives and methods of use thereof | 泰拉科斯有限公司 | 2017-05-24 | — | — | CN | disclosed |
| CN-106458891-A | Carbazole-containing amides, carbamates, and ureas as cryptochrome modulators | 复位治疗公司 | 2017-02-22 | — | — | CN | disclosed |
| CN-105960249-A | Stabilized pharmaceutical formulations of insulin analogues and/or insulin derivatives | 赛诺菲 | 2016-09-21 | — | — | CN | disclosed |
| CN-105899191-A | Stabilized glycerol-free pharmaceutical formulations of insulin analogues and/or insulin derivatives | 赛诺菲 | 2016-08-24 | — | — | CN | disclosed |
| CN-105899190-A | Stabilized pharmaceutical formulations of insulin aspart | 赛诺菲 | 2016-08-24 | — | — | CN | disclosed |
| CN-103338760-B | Anti-diabetic therapy for protecting blood vessels and protecting the heart | 贝林格尔.英格海姆国际有限公司 | 2016-08-17 | — | — | CN | disclosed |
| CN-103781788-B | Quinazoline, its preparation and the purposes in pharmaceutical composition thereof being substituted | 勃林格殷格翰国际有限公司 | 2016-08-17 | — | — | CN | disclosed |
| CN-105753965-A | Conjugate Based Systems For Controlled Drug Delivery | 斯马特塞尔斯公司 | 2016-07-13 | — | — | CN | disclosed |