Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | FPR2 | P25090 | 1/20 | 0.33 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.33 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.33 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15862906 | 0.94 | MAPK1 (0.40) | IDO1POLBCYP1A2CYP2D6TSHR | |
| SCHEMBL15863023 | 0.78 | FPR2 (0.44) | IDO1FPR2PROKR1 | |
| SCHEMBL4598274 | 0.77 | SLC6A4 (0.47) | IDO1POLBFPR2PROKR1 | |
| SCHEMBL29602605 | 0.77 | IDO1 (0.51) | IDO1CYP2D6TSHRFPR2PROKR1 | |
| SCHEMBL15456141 | 0.77 | IDO1 (0.56) | IDO1CYP2D6TSHRFPR2PROKR1 | |
| SCHEMBL15861821 | 0.75 | IDO1 (0.58) | IDO1CYP1A2CYP2D6TSHRFPR2 | |
| SCHEMBL16861642 | 0.75 | IDO1 (0.58) | IDO1CYP1A2CYP2D6TSHRFPR2 | |
| SCHEMBL3951756 | 0.74 | MAPK1 (0.43) | IDO1POLBTSHRFPR2PROKR1 | |
| SCHEMBL16861878 | 0.74 | KDM4E (0.35) | — | |
| SCHEMBL15862913 | 0.74 | PTGS2 (0.38) | IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010141768-A2 | POLYCYCLIC ANTAGONISTS OF LYSOPHOSPHATIDIC ACID RECEPTORS | AMIRA PHARMACEUTICALS, INC. (US) | 2010-12-09 | — | — | WO | disclosed |