Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.62 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.43 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.43 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL489015 | 0.87 | TEAD3 (0.54) | THRBALDH1A1L3MBTL1TSHRHPGD | |
| SCHEMBL69211 | 0.85 | THRB (0.84) | THRBALDH1A1KDM4EL3MBTL1TSHR | |
| SCHEMBL16893759 | 0.83 | THRB (0.69) | THRBALDH1A1FFAR1TSHRHPGD | |
| SCHEMBL21947597 | 0.83 | THRB (0.79) | THRBFFAR1FFAR4 | |
| SCHEMBL22451265 | 0.83 | THRB (0.64) | THRBALDH1A1FFAR1L3MBTL1TSHR | |
| SCHEMBL12219943 | 0.83 | THRB (0.59) | THRBALDH1A1KDM4EMAPTL3MBTL1 | |
| SCHEMBL1031149 | 0.82 | THRB (0.84) | THRBALDH1A1KDM4EL3MBTL1TSHR | |
| SCHEMBL27804950 | 0.82 | THRB (0.57) | THRBNPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL19672885 | 0.82 | THRB (0.53) | THRBNPC1RAB9AALDH1A1KDM4E | |
| Ethylene Glycol SCHEMBL1087639 | 0.81 | THRB (0.58) | THRBALDH1A1TSHRCYP3A4TEAD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100423102-C | Birefringent optical component | KONINKL PHILIPS ELECTRONICS NV (NL) | 2008-10-01 | — | — | CN | disclosed |
| CN-1732520-A | Birefringent optical component | KONINKL PHILIPS ELECTRONICS NV (NL) | 2006-02-08 | — | — | CN | disclosed |