Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 6/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12567540 | 0.84 | THRB (0.48) | THRBNPC1ALDH1A1KDM4ERAB9A | |
| SCHEMBL27615543 | 0.82 | THRB (0.62) | THRBNPC1ALDH1A1KDM4ERAB9A | |
| SCHEMBL8728233 | 0.81 | THRB (0.47) | THRBNPC1ALDH1A1KDM4ERAB9A | |
| SCHEMBL8077109 | 0.81 | PPARG (0.42) | THRBALDH1A1KDM4EMAPTL3MBTL1 | |
| SCHEMBL19295738 | 0.81 | LIPE (0.42) | THRBNPC1ALDH1A1KDM4ERAB9A | |
| SCHEMBL8680303 | 0.81 | THRB (0.50) | THRBNPC1ALDH1A1KDM4ERAB9A | |
| SCHEMBL14088578 | 0.81 | THRB (0.45) | THRBNPC1ALDH1A1KDM4ERAB9A | |
| SCHEMBL25567057 | 0.80 | TSHR (0.53) | THRBNPC1ALDH1A1KDM4ERAB9A | |
| SCHEMBL7268202 | 0.80 | HTT (0.47) | THRBNPC1ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL15523698 | 0.80 | HTT (0.47) | THRBNPC1ALDH1A1MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2755076-B1 | POLYMER-STABILIZED LIQUID CRYSTAL DISPLAY DEVICE AND MANUFACTURING METHOD THEREFOR | BEIJING BOE OPTOELECTRONICS TECH CO LTD (CN) | 2017-12-06 | — | — | EP | disclosed |