Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | BLM | P54132 | 2/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | GRIA1 | P42261 | 5/20 | 0.33 |
| ▸ | GRIA2 | P42262 | 5/20 | 0.33 |
| ▸ | GRIA3 | P42263 | 5/20 | 0.33 |
| ▸ | GRIA4 | P48058 | 5/20 | 0.33 |
| ▸ | GRIK1 | P39086 | 3/20 | 0.33 |
| ▸ | GRIK2 | Q13002 | 3/20 | 0.33 |
| ▸ | GRIK3 | Q13003 | 3/20 | 0.33 |
| ▸ | GRIK5 | Q16478 | 3/20 | 0.33 |
| ▸ | GRM8 | O00222 | 1/20 | 0.33 |
| ▸ | GRM6 | O15303 | 1/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | GSR | P00390 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Histidine SCHEMBL10428659 | 0.94 | ALOX15 (0.39) | ALOX15BLMPMP22KMT2ACYP3A4 | |
| Histidine SCHEMBL10428656 | 0.94 | ALOX15 (0.39) | ALOX15BLMPMP22KMT2ACYP3A4 | |
| Histidine SCHEMBL27597274 | 0.93 | ALOX15 (0.44) | ALOX15BLMPMP22KMT2ACYP3A4 | |
| Histidine SCHEMBL29755 | 0.92 | BLM (0.53) | ALOX15BLMPMP22KMT2ACYP3A4 | |
| Histidine SCHEMBL5712337 | 0.92 | BLM (0.53) | ALOX15BLMPMP22KMT2ACYP3A4 | |
| Histidine SCHEMBL28805947 | 0.90 | SLC7A5 (0.40) | BLMPMP22KMT2ACYP3A4SLC7A5 | |
| Histidine SCHEMBL6426901 | 0.90 | SLC7A5 (0.40) | BLMPMP22KMT2ACYP3A4SLC7A5 | |
| Histidine SCHEMBL668807 | 0.90 | SLC7A5 (0.40) | BLMPMP22KMT2ACYP3A4SLC7A5 | |
| Histidine SCHEMBL6426902 | 0.90 | SLC7A5 (0.40) | BLMPMP22KMT2ACYP3A4SLC7A5 | |
| Histidine SCHEMBL27980643 | 0.89 | ALOX15 (0.40) | ALOX15BLMPMP22KMT2ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1618801-A | D-aminoacylase mutants | DAICEL CHEM (JP) | 2005-05-25 | — | — | CN | disclosed |