Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 3/20 | 0.53 |
| ▸ | PMP22 | Q01453 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.53 |
| ▸ | SLC7A5 | Q01650 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | GRIA2 | P42262 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.39 |
| ▸ | GRIA3 | P42263 | 2/20 | 0.39 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.39 |
| ▸ | GRM8 | O00222 | 1/20 | 0.39 |
| ▸ | GRM6 | O15303 | 1/20 | 0.39 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.39 |
| ▸ | GSR | P00390 | 1/20 | 0.39 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.39 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Histidine SCHEMBL5712337 | 1.00 | BLM (0.53) | BLMPMP22KMT2AALOX15SLC7A5 | |
| Histidine SCHEMBL9389369 | 0.96 | ALOX15 (0.49) | BLMPMP22KMT2AALOX15SLC7A5 | |
| Histidine SCHEMBL2730156 | 0.96 | ALOX15 (0.49) | BLMPMP22KMT2AALOX15SLC7A5 | |
| Histidine SCHEMBL2727906 | 0.96 | ALOX15 (0.49) | BLMPMP22KMT2AALOX15SLC7A5 | |
| Histidine SCHEMBL6534153 | 0.95 | BLM (0.47) | BLMPMP22KMT2AALOX15SLC7A5 | |
| Histidine SCHEMBL28193511 | 0.95 | BLM (0.47) | BLMPMP22KMT2AALOX15SLC7A5 | |
| Histidine SCHEMBL20680473 | 0.95 | BLM (0.47) | BLMPMP22KMT2AALOX15SLC7A5 | |
| Histidine SCHEMBL27730526 | 0.95 | BLM (0.47) | BLMPMP22KMT2AALOX15SLC7A5 | |
| Histidine SCHEMBL17628714 | 0.95 | BLM (0.47) | BLMPMP22KMT2AALOX15SLC7A5 | |
| Histidine SCHEMBL27615311 | 0.94 | BLM (0.46) | BLMPMP22KMT2AALOX15SLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 112 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11896034-B2 | Polypeptides having lysozyme activity, polynucleotides encoding same and uses and compositions thereof | NOVOZYMES A/S (DK) | 2024-02-13 | — | — | US | claimed |
| EP-0594540-B1 | Antiretroviral acyl compounds | CIBA GEIGY AG (CH) | 1998-04-01 | — | — | EP | claimed |
| WO-1992012952-A1 | MALIC ACID DERIVATIVES AND COMPOSITIONS FOR THE TREATMENT OF PSORIASIS | DEXTER CHEMICAL CORPORATION (US) | 1992-08-06 | — | — | WO | claimed |
| CN-112805374-B | Polypeptides having nuclease activity | 诺维信公司 | 2024-06-25 | — | — | CN | disclosed |
| CN-118165957-A | Recombinant nuclease and application thereof | 北京石油化工学院 | 2024-06-11 | — | — | CN | disclosed |
| US-20230257427-A1 | INSECTICIDAL PEPTIDE PRODUCTION, PEPTIDE EXPRESSION IN PLANTS AND COMBINATIONS OF CYSTEINE RICH PEPTIDES | Vestaron Corporation (US) | 2023-08-17 | — | — | US | disclosed |
| US-11692016-B2 | High gene expression yeast strain | SUTERRA LLC | 2023-07-04 | — | — | US | disclosed |
| CN-107936092-B | Peptide domains binding small molecules of industrial interest | 阿切尔丹尼尔斯密德兰公司 | 2022-08-09 | — | — | CN | disclosed |
| US-20220033738-A1 | POLYPEPTIDES HAVING NUCLEASE ACTIVITY | NOVOZYMES A/S (DK) | 2022-02-03 | — | — | US | disclosed |
| US-20220002639-A1 | POLYPEPTIDES HAVING RNASE ACTIVITY | NOVOZYMES A/S (DK) | 2022-01-06 | — | — | US | disclosed |
| US-11208639-B2 | Polypeptides having DNase activity | NOVOZYMES A/S (DK) | 2021-12-28 | — | — | US | disclosed |
| US-20050003388-A1 | Expression vector comprising nucleotide sequences coding hydrolase for use in identifying modulators which treatment and/or prevent nervous system and inflammatory disorders | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2005-01-06 | — | — | US | disclosed |
| US-6753177-B1 | USED IN DRUG SCREENING FOR INHIBITORS OF DOG P-GLYCOPROTEIN (PGP) | BECTON DICKINSON AND COMPANY | 2004-06-22 | — | — | US | disclosed |
| US-20040082030-A1 | Anti-angiogenic polypeptides | WAISMAN DAVID M (CA) | 2004-04-29 | — | — | US | disclosed |
| US-20040033603-A1 | Biotinylation of proteins | SIGMA ALDRICH COMPANY | 2004-02-19 | — | — | US | disclosed |
| EP-1337548-A2 | ANTI-ANGIOGENIC POLYPEPTIDES | Waisman, David M. (CA) | 2003-08-27 | — | — | EP | disclosed |
| EP-1220911-A2 | P-GLYCOPROTEINS AND USES THEREOF | GENTEST CORPORATION (US) | 2002-07-10 | — | — | EP | disclosed |
| WO-2002044328-A2 | ANTI-ANGIOGENIC POLYPEPTIDES | WAISMAN DAVID M (CA) | 2002-06-06 | — | — | WO | disclosed |
| WO-2001023540-A2 | P-GLYCOPROTEINS AND USES THEREOF | GENTEST CORPORATION (US) | 2001-04-05 | — | — | WO | disclosed |
| US-5807980-A | APROTININ DERIVATIVE | CORVAS INTERNATIONAL, INC. (US) | 1998-09-15 | — | — | US | disclosed |