Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27433708 | 0.74 | CES2 (0.35) | CES2CES1FFAR1 | |
| SCHEMBL10086105 | 0.73 | TUBB1 (0.42) | CES2CES1FFAR1 | |
| SCHEMBL6281890 | 0.73 | CES2 (0.38) | CES2CES1FFAR1 | |
| SCHEMBL27509673 | 0.73 | CES2 (0.38) | CES2CES1FFAR1 | |
| SCHEMBL2721538 | 0.71 | CES2 (0.37) | CES2CES1FFAR1 | |
| Hydrochloric Acid SCHEMBL27616168 | 0.71 | CES2 (0.37) | CES2CES1FFAR1 | |
| Bromide SCHEMBL8630598 | 0.70 | CES2 (0.35) | CES2CES1 | |
| Bromide SCHEMBL8630596 | 0.70 | CES2 (0.35) | CES2CES1FFAR1 | |
| SCHEMBL531337 | 0.69 | CES2 (0.52) | CES2CES1 | |
| SCHEMBL30986855 | 0.68 | CES2 (0.39) | CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1637024-A | Olefin polymerization catalyst and olefin polymerization method using the same | MARUZEN PETROCHEM CO LTD (JP) | 2005-07-13 | — | — | CN | disclosed |