SCHEMBL6281890

SCHEMBL6281890

Fc1cc(F)c(F)c(OB(Oc2cc(F)cc(F)c2F)Oc2cc(F)cc(F)c2F)c1

nearest known ligand 0.38

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.38
CES1 P23141 1/20 0.38
ERN1 O75460 1/20 0.31
FFAR1 O14842 1/20 0.31
IDO1 P14902 1/20 0.30
AGXT P21549 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6280829 0.84 CES2 (0.39) CES2CES1ERN1
SCHEMBL30986855 0.84 CES2 (0.39) CES2CES1ERN1
SCHEMBL2141511 0.80
SCHEMBL30213767 0.80
SCHEMBL6519254 0.76 RAPGEF4 (0.32)
SCHEMBL27509673 0.75 CES2 (0.38) CES2CES1FFAR1
SCHEMBL10086105 0.75 TUBB1 (0.42) CES2CES1FFAR1
SCHEMBL2721538 0.73 CES2 (0.37) CES2CES1FFAR1
Hydrochloric Acid SCHEMBL27616166 0.73 CES2 (0.37) CES2CES1FFAR1
Hydrochloric Acid SCHEMBL27616168 0.73 CES2 (0.37) CES2CES1FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1284626-C Fluorinated zwitterionic cocatalyst activators for olefin polymerization EXXONMOBIL CHEM PATENTS INC (US) 2006-11-15 CN disclosed
CN-1227255-C Siloxy substituted cocatalyst activators for olefin polymerization EXXONMOBIL CHEM PATENTS INC (US) 2005-11-16 CN disclosed
US-6919291-B2 Fluorinated zwitterionic cocatalyst activators for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2005-07-19 US disclosed
US-6861384-B2 Process for preparation of a salt-like chemical compound and its use in catalyst systems for preparing polyolefins BASELL POLYOLEFINE GMBH (DE) 2005-03-01 US disclosed
CN-1178960-C Siloxy substituted cocatalyst activators for olefin polymerization 埃克森美孚化学专利公司 2004-12-08 CN disclosed
CN-1172964-C Nitrogen-containing group 13 anionic compound for olefin polymerization ����ɭ���ڻ�ѧר����˾ 2004-10-27 CN disclosed
US-20040110631-A1 Fluorinated zwitterionic cocatalyst activators for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. 2004-06-10 US disclosed
US-20040072975-A1 Salt-like chemical compound, its preparation and its use in catalyst systems for preparing polyolefins BASELL POLYPROPYLEN GMBH (DE) 2004-04-15 US disclosed
US-20040048992-A1 Process for preparation of salt-like chemical compound, and its use in catalyst systems for preparing polyolefins EQUISTAR CHEMICALS, LP 2004-03-11 US disclosed
CN-1477995-A Fluorinated zwitterionic cocatalyst activators for olefin polymerization 埃克森美孚化学专利公司 2004-02-25 CN disclosed
EP-1349653-A2 FLUORINATED ZWITTERIONIC COCATALYST ACTIVATORS FOR OLEFIN POLYMERIZATION ExxonMobil Chemical Patents Inc. (US) 2003-10-08 EP disclosed
CN-1437607-A Siloxy substituted cocatalyst activators for olefin polymerization EXXONMOBIL CHEM PATENTS INC (US) 2003-08-20 CN disclosed
CN-1427849-A Nitrogen-Containing group-13 anionic compounds for olefin polymerization EXXONMOBIL CHEM PATENTS INC (US) 2003-07-02 CN disclosed
US-20030069426-A1 Saline chemical composition, method for producing the same and the use thereof in catalyst systems for producing polyolefins SCHOTTEK JORG (DE) 2003-04-10 US disclosed
WO-2002036639-A2 FLUORINATED ZWITTERIONIC COCATALYST ACTIVATORS FOR OLEFIN POLYMERIZATION EXXONMOBIL CHEMICAL PATENTS INC. (US) 2002-05-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030069426-A1 Saline chemical composition, method for producing the same and the use thereof in catalyst systems for producing polyolefins CLIC1, HACL2, ADH1C CES2 284/4885CES1 1021/4885ERN1 1152/4885
US-20040110631-A1 Fluorinated zwitterionic cocatalyst activators for olefin polymerization FZD7, FOS, COG4 CES2 1566/4885CES1 3081/4885ERN1 3070/4885
US-20040048992-A1 Process for preparation of salt-like chemical compound, and its use in catalyst systems for preparing polyolefins CLIC1, HACL2, RFC1 CES2 522/4885CES1 979/4885ERN1 830/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.