Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28218016 | 0.88 | ALDH1A1 (0.49) | ALDH1A1MAPTHPGDL3MBTL1MAPK1 | |
| SCHEMBL27616536 | 0.84 | NR1H2 (0.44) | ALDH1A1MAPTL3MBTL1TSHRKMT2A | |
| SCHEMBL24514516 | 0.84 | ALDH1A1 (0.50) | ALDH1A1MAPTHPGDL3MBTL1MAPK1 | |
| SCHEMBL9317602 | 0.80 | ALDH1A1 (0.53) | ALDH1A1MAPTHPGDL3MBTL1MAPK1 | |
| SCHEMBL9632869 | 0.80 | TP53 (0.46) | ALDH1A1MAPTL3MBTL1CYP3A4TSHR | |
| SCHEMBL9632865 | 0.80 | TP53 (0.46) | ALDH1A1MAPTL3MBTL1CYP3A4TSHR | |
| SCHEMBL18510056 | 0.77 | ALDH1A1 (0.56) | ALDH1A1MAPTHPGDL3MBTL1MAPK1 | |
| SCHEMBL26290931 | 0.77 | ALDH1A1 (0.56) | ALDH1A1MAPTHPGDL3MBTL1MAPK1 | |
| SCHEMBL20589964 | 0.76 | CETP (0.52) | ALDH1A1HPGDL3MBTL1MAPK1TDP1 | |
| SCHEMBL20589967 | 0.76 | CETP (0.52) | ALDH1A1HPGDL3MBTL1MAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100355900-C | Method for enzyme catalytic resolution of N substituted alpha amino acid | UNIV JILIN (CN) | 2007-12-19 | — | — | CN | disclosed |
| CN-1632129-A | Method for enzyme catalytic resolution of N substituted alpha amino acid | UNIV JILIN (CN) | 2005-06-29 | — | — | CN | disclosed |