Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27616535 | 0.88 | ALDH1A1 (0.46) | ALDH1A1MAPTHPGDL3MBTL1KMT2A | |
| SCHEMBL11826311 | 0.83 | NR1H2 (0.52) | ALDH1A1MAPTL3MBTL1KMT2ATSHR | |
| SCHEMBL9317602 | 0.83 | ALDH1A1 (0.53) | ALDH1A1MAPTHPGDL3MBTL1KMT2A | |
| SCHEMBL11655001 | 0.80 | TDP1 (0.45) | ALDH1A1MAPTL3MBTL1KMT2ATDP1 | |
| SCHEMBL20272638 | 0.80 | ALDH1A1 (0.50) | ALDH1A1MAPTHPGDL3MBTL1KMT2A | |
| SCHEMBL26290931 | 0.79 | ALDH1A1 (0.56) | ALDH1A1MAPTHPGDL3MBTL1KMT2A | |
| SCHEMBL18510056 | 0.79 | ALDH1A1 (0.56) | ALDH1A1MAPTHPGDL3MBTL1KMT2A | |
| SCHEMBL3343176 | 0.79 | ALDH1A1 (0.50) | ALDH1A1MAPTKMT2ALMNATSHR | |
| SCHEMBL3343171 | 0.79 | ALDH1A1 (0.50) | ALDH1A1MAPTKMT2ALMNATSHR | |
| SCHEMBL7168924 | 0.78 | ALDH1A1 (0.47) | ALDH1A1MAPTHPGDL3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108026271-A | The macromolecule conjugate of 6 coordinate platinum complex | 日本化药株式会社 | 2018-05-11 | — | — | CN | disclosed |