Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2263049 | 0.85 | KCNA3 (0.34) | — | |
| SCHEMBL2265198 | 0.76 | MAP2K1 (0.34) | MAOA | |
| SCHEMBL27598093 | 0.70 | GYS1 (0.32) | — | |
| SCHEMBL29287469 | 0.69 | TRPA1 (0.33) | MAOATRPA1 | |
| SCHEMBL18876041 | 0.69 | TRPA1 (0.36) | MAOATRPA1 | |
| SCHEMBL6304857 | 0.69 | TRPA1 (0.33) | MAOATRPA1 | |
| SCHEMBL5253941 | 0.69 | CYP2A6 (0.37) | MAOATRPA1 | |
| SCHEMBL16089560 | 0.66 | MAP2K1 (0.34) | MAOATRPA1 | |
| SCHEMBL2265856 | 0.65 | MGLL (0.35) | MAOA | |
| SCHEMBL2260703 | 0.64 | KCNA3 (0.33) | MAOATRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1639152-A | Pyrrole-2, 5-dione derivatives and their use as GSK-3 inhibitors | LILLY CO ELI (US) | 2005-07-13 | — | — | CN | disclosed |