Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | MEP1A | Q16819 | 1/20 | 0.33 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | DRD5 | P21918 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7423782 | 0.83 | TRPA1 (0.42) | MEN1KMT2AFFAR1GLAMEP1A | |
| SCHEMBL3033002 | 0.80 | MEN1 (0.36) | MEN1KMT2ATAAR1FFAR1GLA | |
| SCHEMBL2058688 | 0.80 | GLA (0.47) | TDP1MEN1KMT2AFFAR1GLA | |
| SCHEMBL910177 | 0.80 | DRD2 (0.40) | MEN1KMT2AGLADRD2DRD1 | |
| SCHEMBL4427688 | 0.78 | TDP1 (0.65) | TDP1MEN1KMT2ATAAR1DRD2 | |
| SCHEMBL6267027 | 0.77 | MEN1 (0.68) | MEN1KMT2AFFAR1GLAMEP1A | |
| SCHEMBL3032722 | 0.77 | XIAP (0.46) | — | |
| SCHEMBL10490694 | 0.77 | HTR2B (0.35) | MEN1KMT2ATAAR1FFAR1GLA | |
| SCHEMBL6853158 | 0.76 | MGLL (0.34) | MEN1KMT2AFFAR1GLACNR1 | |
| SCHEMBL17103228 | 0.76 | GLA (0.34) | MEN1KMT2ATAAR1FFAR1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1684966-A | Novel adenine compound and use thereof | SUMITOMO PHARMA (JP) | 2005-10-19 | — | — | CN | disclosed |