Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.32 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.31 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | BUB1 | O43683 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21768492 | 0.81 | GPR119 (0.35) | MAPK1EPHX2CHRM2CHRM1CHRM3 | |
| SCHEMBL25434706 | 0.78 | DDB1 (0.32) | MAPK1EPHX2CHRM2CHRM1CHRM3 | |
| SCHEMBL14777493 | 0.78 | DDB1 (0.32) | MAPK1EPHX2CHRM2CHRM1CHRM3 | |
| SCHEMBL30073378 | 0.72 | EPHX2 (0.33) | MAPK1EPHX2CHRM2CHRM1CHRM3 | |
| SCHEMBL5792538 | 0.71 | BUB1 (0.33) | BUB1 | |
| SCHEMBL25784525 | 0.69 | SMN1; SMN2 (0.35) | MAPK1EPHX2 | |
| SCHEMBL14635333 | 0.66 | BUB1 (0.33) | MAPK1CHRM2CHRM1CHRM3GPR119 | |
| SCHEMBL27598573 | 0.65 | BUB1 (0.32) | BUB1 | |
| SCHEMBL28611968 | 0.65 | CHRM2 (0.40) | EPHX2CHRM2CHRM1CHRM3GPR119 | |
| SCHEMBL680915 | 0.64 | RORC (0.44) | GPR119KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1633446-A | Novel peptides as inhibitors of hepatitis C virus NS 3-serine protease | SCHERING CORP (US) | 2005-06-29 | — | — | CN | disclosed |