Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | CASP3 | P42574 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.53 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.53 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | SGMS1 | Q86VZ5 | 1/20 | 0.49 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.49 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27617791 | 0.92 | CYP19A1 (0.55) | NPC1CASP3RAB9ASENP8SENP7 | |
| SCHEMBL27617818 | 0.81 | LMNA (0.43) | TDP1MAPK1MAPTHPGDTSHR | |
| SCHEMBL5793080 | 0.81 | CYP19A1 (0.65) | NPC1CASP3RAB9ASENP8SENP7 | |
| SCHEMBL27617799 | 0.78 | CYP19A1 (0.49) | TDP1MAPK1CYP19A1MAPTALDH1A1 | |
| SCHEMBL28757643 | 0.78 | CYP19A1 (0.45) | TDP1MAPK1SMN1; SMN2CYP19A1MAPT | |
| SCHEMBL27613201 | 0.76 | TDP1 (0.77) | NPC1CASP3RAB9ASENP8SENP7 | |
| SCHEMBL28754643 | 0.75 | CYP19A1 (0.47) | RAB9ATDP1MAPK1CYP19A1MAPT | |
| SCHEMBL6761458 | 0.74 | HPGD (0.50) | TDP1SMN1; SMN2CYP19A1MAPTALDH1A1 | |
| SCHEMBL27617796 | 0.74 | FFAR1 (0.45) | CYP19A1MAPTGAASLC5A1SLC5A2 | |
| Dihydrochalcone SCHEMBL29359372 | 0.74 | CYP19A1 (0.80) | NPC1RAB9ATDP1ACHESGMS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1717409-A | Pyrazolonaphthyridine derivative | GRELAN PHARMACEUTICAL CO (JP) | 2006-01-04 | — | — | CN | disclosed |