Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | FNTA | P49354 | 1/20 | 0.41 |
| ▸ | FNTB | P49356 | 1/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | SHBG | P04278 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27617791 | 0.85 | CYP19A1 (0.55) | MAPTMEN1KMT2AHPGDHTT | |
| SCHEMBL27636908 | 0.81 | NPC1 (0.59) | LMNAMEN1KMT2AHPGDHTT | |
| SCHEMBL27617814 | 0.81 | NPC1 (0.53) | MAPTHPGDHTTGAAMAPK1 | |
| SCHEMBL27636901 | 0.81 | CTBP2 (0.43) | LMNAMAPTMEN1KMT2AHPGD | |
| SCHEMBL27617803 | 0.80 | CTBP2 (0.48) | LMNAMEN1KMT2AHPGDHTT | |
| SCHEMBL27636905 | 0.79 | ENPP2 (0.39) | LMNAMAPTMEN1KMT2AHPGD | |
| SCHEMBL8376 | 0.78 | HPGD (0.56) | LMNAMAPTMEN1KMT2AHPGD | |
| SCHEMBL29586388 | 0.78 | HPGD (0.56) | LMNAMAPTMEN1KMT2AHPGD | |
| SCHEMBL5462574 | 0.76 | TDP1 (0.67) | LMNAMAPTKMT2AHPGDL3MBTL1 | |
| SCHEMBL27617822 | 0.76 | CA1 (0.48) | LMNAMAPTMEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1717409-A | Pyrazolonaphthyridine derivative | GRELAN PHARMACEUTICAL CO (JP) | 2006-01-04 | — | — | CN | disclosed |