Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15427662 | 0.80 | SIRT2 (0.45) | CYP19A1MEN1KMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL28585713 | 0.80 | CYP19A1 (0.51) | CYP19A1MEN1KMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL29531283 | 0.80 | CYP19A1 (0.51) | CYP19A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL28722325 | 0.80 | CYP19A1 (0.51) | CYP19A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL6461863 | 0.79 | ALOX12 (0.45) | CYP19A1MEN1KMT2AL3MBTL1 | |
| Alpha-Phenyl-Gamma-Butyrolactone SCHEMBL6771142 | 0.78 | CYP19A1 (0.44) | CYP19A1KMT2A | |
| Alpha-Phenyl-Gamma-Butyrolactone SCHEMBL7909086 | 0.78 | CYP19A1 (0.44) | CYP19A1KMT2A | |
| Alpha-Phenyl-Gamma-Butyrolactone SCHEMBL576473 | 0.78 | CYP19A1 (0.44) | CYP19A1KMT2A | |
| SCHEMBL28722327 | 0.76 | DDB1 (0.55) | CYP19A1 | |
| SCHEMBL10174634 | 0.76 | SMN1; SMN2 (0.37) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1615155-B | Anti-proliferative composition | NUTRICIA NV | 2012-06-27 | — | — | CN | disclosed |
| CN-1615155-A | Anti-proliferative composition | NUTRICIA NV (NL) | 2005-05-11 | — | — | CN | disclosed |