Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 4/20 | 0.44 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.43 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.43 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.41 |
| ▸ | CTRC | Q99895 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CFTR | P13569 | 1/20 | 0.39 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alpha-Phenyl-Gamma-Butyrolactone SCHEMBL7909086 | 1.00 | CYP19A1 (0.44) | CYP19A1DDB1CRBNCTRB1CTRC | |
| Alpha-Phenyl-Gamma-Butyrolactone SCHEMBL6771142 | 1.00 | CYP19A1 (0.44) | CYP19A1DDB1CRBNCTRB1CTRC | |
| Alpha-Phenyl-Gamma-Butyrolactone SCHEMBL28579210 | 0.91 | CYP19A1 (0.40) | CYP19A1DDB1CRBNCTRB1CTRC | |
| SCHEMBL576991 | 0.88 | TP53 (0.42) | CYP19A1DDB1CRBNCTRB1CTRC | |
| SCHEMBL576404 | 0.86 | TP53 (0.41) | CYP19A1DDB1CRBNCTRB1CTRC | |
| Alpha-Phenyl-Gamma-Butyrolactone SCHEMBL28588955 | 0.84 | CYP19A1 (0.43) | CYP19A1DDB1CRBNCTRB1 | |
| Alpha-Phenyl-Gamma-Butyrolactone SCHEMBL28591531 | 0.83 | ALDH1A1 (0.51) | CYP19A1DDB1CRBNCTRB1CTRC | |
| SCHEMBL6461863 | 0.80 | ALOX12 (0.45) | CYP19A1KMT2AMAPK1 | |
| SCHEMBL10393997 | 0.80 | TP53 (0.42) | CYP19A1KMT2A | |
| SCHEMBL576857 | 0.80 | CYP19A1 (0.45) | CYP19A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 114 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118580203-A | Preparation method of 5-benzoyl dihydrofuran-2 (3H) -ketone and derivative thereof | 阜阳师范大学 | 2024-09-03 | — | — | CN | claimed |
| CN-113088393-B | Fenghua Yulu essence | 江苏省农业科学院 | 2024-02-27 | — | — | CN | claimed |
| CN-107721956-B | Benzobutyrolactone derivative, synthesis method and application thereof in preparing bactericide | 西北农林科技大学 | 2021-02-12 | — | — | CN | claimed |
| US-20080311478-A1 | Lithium Secondary Battery | MITSUBISHI CHEMICAL CORPORATION (JP) | 2008-12-18 | — | — | US | claimed |
| EP-1892789-A1 | LITHIUM SECONDARY BATTERY | Mitsubishi Chemical Corporation (JP) | 2008-02-27 | — | — | EP | claimed |
| EP-4662204-A2 | TELOMERASE INHIBITOR COMPOUNDS | Geron Corporation (US) | 2025-12-17 | — | — | EP | disclosed |
| US-20250302803-A1 | ARYL-SUBSTITUTED ACETAMIDE AND PYRROLIDIN-2-ONE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF SEIZURES | UNIVERSITY OF HOUSTON SYSTEM (US) | 2025-10-02 | — | — | US | disclosed |
| US-12357610-B2 | Aryl-substituted acetamide and pyrrolidin-2-one derivatives and their use for the treatment of seizures | UNIVERSITY OF HOUSTON SYSTEM (US) | 2025-07-15 | — | — | US | disclosed |
| US-20240343713-A1 | TELOMERASE INHIBITOR COMPOUNDS | BIOPHARMA CREDIT PLC [COLLATERAL AGENT] (GB) | 2024-10-17 | — | — | US | disclosed |
| WO-2024168165-A2 | TELOMERASE INHIBITOR COMPOUNDS | GERON CORPORATION (US) | 2024-08-15 | — | — | WO | disclosed |
| US-20230414566-A1 | ARYL-SUBSTITUTED ACETAMIDE AND PYRROLIDIN-2-ONE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF SEIZURES | UNIVERSITY OF HOUSTON SYSTEM (US) | 2023-12-28 | — | — | US | disclosed |
| US-11806333-B2 | Aryl-substituted acetamide and pyrrolidin-2-one derivatives and their use for the treatment of seizures | UNIVERSITY OF HOUSTON SYSTEM (US) | 2023-11-07 | — | — | US | disclosed |
| WO-1994012487-A1 | PROCESS FOR THE PREPARATION OF α-ARYL-η-BUTYROLACTONES | JOHN WYETH & BROTHER LIMITED (GB) | 1994-06-09 | — | — | WO | disclosed |
| EP-0400584-A2 | Geminally substituted thiaheterocyclic carboxylic acids and derivatives thereof | E.R. SQUIBB & SONS, INC. (US) | 1990-12-05 | — | — | EP | disclosed |
| US-4975452-A | Geminally substituted thiaheterocyclic carboxylic acids and derivatives thereof | E. R. SQUIBB & SONS, INC. (US) | 1990-12-04 | — | — | US | disclosed |
| US-4783473-A | ANTICOAGULANTS, VASODILATORS, BRONCHODILATORS | E. R. SQUIBB & SONS, INC. (US) | 1988-11-08 | — | — | US | disclosed |
| EP-0107599-B1 | PROCESS FOR THE PREPARATION OF SATURATED LINEAR ESTERS BY CARBONYLATION OF MONOOLEFINIC COMPOUNDS | RHONE-POULENC CHIMIE DE BASE (FR) | 1985-12-11 | — | — | EP | disclosed |
| EP-0107599-A1 | Process for the preparation of saturated linear esters by carbonylation of monoolefinic compounds | RHONE-POULENC CHIMIE DE BASE (FR) | 1984-05-02 | — | — | EP | disclosed |
| US-4351839-A | Fungicidal 2-aryl-2-1-H-azoyl-(alkyl)-gamma-butyrolactones | ROHM AND HAAS COMPANY (US) | 1982-09-28 | — | — | US | disclosed |
| US-3963757-A | Process for the preparation of lactones | PHILLIPS PETROLEUM COMPANY (US) | 1976-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240343713-A1 | TELOMERASE INHIBITOR COMPOUNDS | TERT, POT1, TERF2 | CYP19A1 870/4885DDB1 194/4885CRBN 711/4885 |
| US-12357610-B2 | Aryl-substituted acetamide and pyrrolidin-2-one derivatives and their use for the treatment of seizures | AADAC, GABRB2, GABARAPL2 | CYP19A1 385/4885DDB1 2490/4885CRBN 2914/4885 |
| US-20250302803-A1 | ARYL-SUBSTITUTED ACETAMIDE AND PYRROLIDIN-2-ONE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF SEIZURES | AADAC, GABRB2, GABARAPL2 | CYP19A1 385/4885DDB1 2490/4885CRBN 2914/4885 |
| US-20230414566-A1 | ARYL-SUBSTITUTED ACETAMIDE AND PYRROLIDIN-2-ONE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF SEIZURES | AADAC, GABRB2, GABARAPL2 | CYP19A1 385/4885DDB1 2490/4885CRBN 2914/4885 |
| US-11806333-B2 | Aryl-substituted acetamide and pyrrolidin-2-one derivatives and their use for the treatment of seizures | AADAC, GABRB2, GABARAPL2 | CYP19A1 385/4885DDB1 2490/4885CRBN 2914/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.